重庆医学2017，Vol.46Issue(1)：68-71,4.DOI:10.3969/j.issn.1671-8348.2017.01.015
3例毛母细胞瘤临床病理分析
Clinicopathological analysis of 3 cases of trichoblastoma
陈广业 1张醇 2朱鸿静 1张宏利 1刘家君 1杨清1
作者信息
- 1. 重庆市荣昌区人民医院病理科 402460
- 2. 武警重庆市总队医院病理科 400061
- 折叠
摘要
Abstract
Objective To summarize and study the clinicopathologic features,diagnosis and differential diagnosis of tricho-blastoma (TB).Methods The clinicopathological characteristics,histomorphology features and immunophenotype features of TB and differential diagnosis with multiple diseases in 3 cases of TB were retrospectively analyzed;moreover,5 cases of basal cell carci-noma were selected and performed the immunophenotype detection,which focused on the differential diagnosis with TB.Results The masses in 3 cases were located under the skin without connecting with the epidermis and were composed of basal-like cells with palisade arrangement of peripheral cells.The case 1 showed unequal-sized multiple cyst cavities and pigment deposition and was di-agnosed as pigmented TB.The papillary mesenchymal bodies were found in case 2,which was diagnosed as TB.The basal cells of tumor in case 3 distributed as palisade arrangement and formed the wave structure,which was diagnosed as rippled-pattern TB.AR in 3 cases and Bcl-2 in 2 cases were negative expression,CK20 in 1 case was sporadically positive,CD10 stroma and papillary struc-ture in 3 cases were positive,paliform-like arrange tumor cells CD10 around basal cell carcinomas in 5 cases were positive,AR in 4 cases was positive,Bcl-2 in 3 cases was positive and CK20 in 5 cases was negative.Conclusion TB is a benign tumor derived from the hair follicle germinal epithelium with a good prognosis after complete resection and the differential diagnosis focuses on basal cell carcinomas.关键词
毛母细胞瘤/基底样细胞/栅栏状/原始毛乳头样结构/基底细胞癌/免疫组织化学Key words
trichoblastoma/basal-like cells/palisade arrangement/papillary mesenchymal bodies/basal cell carcinomas/im-munohistochemistry分类
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陈广业,张醇,朱鸿静,张宏利,刘家君,杨清..3例毛母细胞瘤临床病理分析[J].重庆医学,2017,46(1):68-71,4.
