福建农业学报2016，Vol.31Issue(11)：1139-1144,6.DOI:10.19303/j.issn.1008-0384.2016.11.001
猪伪狂犬病毒 gB 基因序列分析
Sequence Analysis on gB Gene from Pseudorabies Virus
摘要
Abstract
Since 201 1,variant pseudorabies (PR)had occurred to the Bartha-k61 vaccinated pigs on farms in most provinces in China.The traditional Bartha-k61 vaccine could not prevent those pigs from contracting the viral disease.As a result,substantial financial losses had incurred to the porcine industry.A previous study indicated that there existed distinctive variations between the gE gene of the typical PR virus (PRV)and that of the variant PRV.For comparison,the sequence of the gB gene of the typical PRV was downloaded from GenBank.It was found that at Positions 395, 453, 562, and 739 they showed different characteristics, and their nucleotide homology was 98.1%-100% and amino acids 96.1%-100%.A phylogenetic analysis suggested that the viruses were from two different branches and differed significantly depending upon their geographic origins.In China,these viruses had different sub-branches.And,the variant PRV shared a same sub-branch in origin with the newly identified Nyctereutes procyonoides and Yorkshire Terrier PR.The information obtained would be valuable for studying biological functions of gB as well as origin-tracing on variant PRV.关键词
猪伪狂犬病毒/gB 基因/序列分析Key words
Pseudorabies virus/gB gene/sequence analysis分类
农业科技引用本文复制引用
陈如敬,魏宏,周伦江,吴学敏,黄晓凤,车勇良,严山,王晨燕,王隆柏,刘玉涛..猪伪狂犬病毒 gB 基因序列分析[J].福建农业学报,2016,31(11):1139-1144,6.基金项目
福建省科技计划项目---省属公益类科研院所基本科研专项(2014R1023-13、2014R1023-16) （2014R1023-13、2014R1023-16）
