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首页|期刊导航|国际医药卫生导报|腹腔镜辅助远端胃大部切除术与传统开腹胃癌切除术对老年胃癌患者血清TNF-α、IL-6、CRP的影响及短期疗效比较

腹腔镜辅助远端胃大部切除术与传统开腹胃癌切除术对老年胃癌患者血清TNF-α、IL-6、CRP的影响及短期疗效比较

刘旭忠 韩松

国际医药卫生导报2017,Vol.23Issue(1):65-67,72,4.
国际医药卫生导报2017,Vol.23Issue(1):65-67,72,4.DOI:10.3760/cma.j.issn.1007-1245.2017.01.0021

腹腔镜辅助远端胃大部切除术与传统开腹胃癌切除术对老年胃癌患者血清TNF-α、IL-6、CRP的影响及短期疗效比较

Short term efficacy of laparoscopic assisted distal gastrectomy versus traditional open surgery for elderly patients with gastric cancer and its effect on serum levels of TNF-α, IL-6, and CRP

刘旭忠 1韩松1

作者信息

  • 1. 266300 胶州市人民医院普外科
  • 折叠

摘要

Abstract

Objective To explore the short term efficacy of laparoscopic assisted distal gastrectomy versus traditional open surgery for elderly patients with gastric cancer and its effect on serum levels ofTNF-α,IL-6,and CRP.Methods 52 elderly patients with distal gastric cancer treated at our hospital were collected and were randomly divided into an experimental group and a control group,26 cases for each group.The control group were treated by traditional open surgery and the experimental group laparoscopic assisted distal gastrectomy.After the treatment,the serum levels ofturnor necrosis factor α (TNF-α),intefleukin-6 (IL-6),and C reactive protein (CRP),the intra-operative conditions,the short-term-outcome-related indicators,and the incidence of complications were compared between these two groups.Results The operation time was (266.57±38.07) min in the experimental group,which was longer than that in the control group;the intra-operative bleeding volume was (172.65±24.06) ml,which was lower than that in the control group;with statistical differences (P < 0.05).The postoperative ventilation time,the first feeding time,and the postoperative hospitalization time were significantly shorter in the experimental group than in the control group,with statistical differences (P < 0.05).The serum levels of TNF-α,IL-6,and CRP were lower in the experimental group than in the control group (P < 0.05).The total incidence of postoperative complications was 11.53% in the experimental group and was 38.46% in the control group,with a statistical difference (P < 0.01).Conclusions Compared with traditional open surgery for gastric cancer,laparoscopic assisted distal gastrectomy for elderly patients with gastric cancer has longer operation time but lower intra-operative bleeding volume,better short-term curative effect,and fewer postoperative complications,so it is worth being clinically gerneralized.

关键词

腹腔镜辅助远端胃大部切除术/传统开腹胃癌切除术/老年胃癌/短期疗效/并发症

Key words

Laparoscopic assisted distal gastrectomy/Traditional open surgery for gastric cancer/Elderly patients with gastric cancer/Short-term curative effect/Complications

引用本文复制引用

刘旭忠,韩松..腹腔镜辅助远端胃大部切除术与传统开腹胃癌切除术对老年胃癌患者血清TNF-α、IL-6、CRP的影响及短期疗效比较[J].国际医药卫生导报,2017,23(1):65-67,72,4.

国际医药卫生导报

1007-1245

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