Abstract
Objective To observe the clinical outcome of preemptive analgesia with ropivacaine complex liquid for postoperative pain management in patients undergoing thoracolumbar posterior surgery.Methods 170 patients undergoing thoracolumbar posterior surgery were randomly divided in two groups:group A (control group,n=85) and group B (ropivacaine complex liquid group,n=85).The efficacy of postoperative pain control was assessed with visual analogue scale (VAS,0-10),And various postoperative things were monitored for analysis,such as the intranperative blood loss,pain scores 6 h,12 h,24 h,36 h,48 h,3 d,7 d after operation,the time to first supplemental analgesic consumption,the total person-time of analgesic consumption,and the side effect.Resuits There was no statistically significant difference in intraoperative blood loss between group B and group A [(315.29±222.81)ml vs.(348.24±308.16)ml,P＞0.05].Pain scores in group A 6 h,12 h,24 h,36 h,48 h,3 d,7 d after operation were (3.00± 1.31),(2.81 ±0.92),(2.39±0.60),(2.11±0.89),(1.71 ±0.59),(1.53±0.98),(1.16±0.65),those in group B were (1.91±1.28),(1.74±0.86),(1.59±0.66),(1.44±0.59),(1.21±0.66),(0.79±0.66),(0.40±0.21),the analgesic effect in group B at each time point were significantly better than those in group A (P＜0.05).The time to first supplemental analgesic consumption in group B was longer than that in group A (P＜0.05).The person-time of tramadol hydrochloride consumption in group B was significantly lower than that in group A (13 vs.47,P＜0.05),there was no statistically significant difference in the person-time of pethidine consumption between group B and group A (4 vs.5,P＞0.05).The total person-time of side effects in group B was significantly lower than that in group A (13 vs.30,P＜0.05).Conclusion Preemptive analgesia with ropivacaine complex liquid is effective for postoperative pain management after thoracolumbar posterior surgery,which can lower the dose of opioids as well as the rate of side effects.关键词
罗哌卡因/超前镇痛/胸腰椎后路手术/术后疼痛Key words
Ropivacaine/Preemptive analgesia/Thoracolumbar posterior surgery/Postoperative pain
