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颌面头颈部骨肉瘤化学治疗的研究进展

李晓 季彤

国际口腔医学杂志2017,Vol.44Issue(1):83-86,4.
国际口腔医学杂志2017,Vol.44Issue(1):83-86,4.DOI:10.7518/gjkq.2017.01.017

颌面头颈部骨肉瘤化学治疗的研究进展

Chemotherapy in the treatment of osteosarcoma in oral maxillofacial-head and neck region

李晓 1季彤2

作者信息

  • 1. 上海交通大学医学院附属第九人民医院口腔颌面头颈肿瘤科
  • 2. 上海市口腔医学重点实验室 上海200011
  • 折叠

摘要

Abstract

Osteosarcoma is one of the rare malignant tumors in the maxillofacial region. Synthetic sequential therapy including radical resection and adjuvant radio-chemotherapy is the most effective currently. Chemotherapy is an important part in synthetic sequential therapy. In the existing chemotherapy regimens, traditional chemotherapy such as MAP(methotrexate, adriacin, cisplatin) plays a key role in the treatment of osteosarcoma in oral maxillofacial-head and neck region. In addition, some other regimens such as neoadjuvant chemotherapy, electrochemical therapy are also proposed in recent years, but their effectiveness remains to be investigated. Chemotherapy has a significant effect on improving the prognosis of osteosarcoma. With the gradual development of the cognition of osteosarcoma molecular biology in recent years, it has become a new trend to study the chemical drugs for tumor cells in the level of molecular biology. This paper reviews the application of chemotherapy in the treatment of osteosarcoma in oral and maxillofacial-head and neck region.

关键词

骨肉瘤/化学疗法/口腔颌面部

Key words

osteosarcoma/chemotherapy/oral and maxillofacial region

分类

医药卫生

引用本文复制引用

李晓,季彤..颌面头颈部骨肉瘤化学治疗的研究进展[J].国际口腔医学杂志,2017,44(1):83-86,4.

基金项目

上海高校高峰高原学科建设项目 ()

国际口腔医学杂志

OACSCDCSTPCD

1673-5749

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