国际口腔医学杂志2017，Vol.44Issue(1)：118-123,6.DOI:10.7518/gjkq.2017.01.024
粪肠球菌和变异链球菌脂磷壁酸的生物学活性
Biological activity of Enterococcus faecalis and Streptococcus mutans lipoteichoic acid
摘要
Abstract
Enterococcus faecalis(E. faecalis) is commonly detected in refractory and chronic periapical periodontal infections and is one of the main pathogenic bacteria in the root canal. Streptococcus mutans(S. mutans) is the main pathogenic bacteria caused by dental caries. E. faecalis and S. mutans virulence factors of lipoteichoic acid(LTA) can promote cells to secrete inflammatory factor, which leads to inflammation, promotes the absorption of periapical alveolar bone, and contributes to bacterial adhesion on tooth surface and biofilm formation. E. faecalis and S. mutans LTA in pathogenic bacteria is important, but its ultimate function is unclear. Therefore, this study investigates the pathogenic mechanism and molecular structure of LTA to understand the blockage of pathogenic pathway and thus reduce its pathogenicity.关键词
粪肠球菌/变异链球菌/脂磷壁酸/生物学活性/致病机制Key words
Enterococcus faecalis/Streptococcus mutans/lipoteichoic acid/biological activity/pathogenic mechanism分类
医药卫生引用本文复制引用
刘琨,侯本祥..粪肠球菌和变异链球菌脂磷壁酸的生物学活性[J].国际口腔医学杂志,2017,44(1):118-123,6.基金项目
国家自然科学基金 （）
