李琳 1罗德红 1胡镭 1赵燕风 1郭炜 1林蒙 1赵心明 1周纯武1
作者信息
- 1. 北京协和医学院中国医学科学院肿瘤医院影像诊断科，北京 100021
- 折叠
摘要
Abstract
Objective The aim of the current study was to retrospectively analyze spectral CT images of papillary thyroid microcarcinoma (PTMC) and to evaluate the diagnostic value for PTMC. Methods Thirty-three cases (35 lesions) with pathological confirmed PTMC from 2015 to 2016 were included in this retrospective study. All the patients underwent spectral CT scan using Discovery CT 750 HD scanner. All the spectral CT images were divided into 3 groups:polychromatic image (group A), optimal monochromatic image (group B), and the fused image which blended optimal monochromatic image and iodine-based material decomposition image together (group C). The paired t-test was used to compare the objective evaluations of image quality in group A and group B. The subjective scores of three groups were compared by one-way ANOVA and multiple comparisons using LSD-t test. The imaging features and spectral parameters of all the lesions were analyzed and measured. Result The contrast-to-noise ratio of optimal monochromatic image was higher than that of polychromatic image, and the noise of optimal monochromatic image was lower than that of polychromatic image, and the differences were significant (P<0.05). The detection rate of the 3 groups of images for microcarcinoma lesions were 91.4%, 97.1%, and 100%, respectively;the subjective scores of the 3 groups of images were 2.54 ±1.15,3.31 ±0.93, and 3.46 ±0.74, respectively. The detection ability of fused image was better than that of polychromatic image andwas similar to that of optimal monochromatic image.The characteristics of microcarcinomaincludedirregular shape(19 cases, 54.3%), indistinct margin (24 cases, 68.6%), heterogeneous density (24 cases, 68.6%), presenceof microcalcification (16 cases, 45.7%), and lymph node metastasis (20 cases, 57.1%). The lesions’ average iodine concentration, normalized iodine concentration, and the average spectral HU curve slope values were 2.50 ±1.03mg/mL, 0.33 ±0.14, and 2.99 ±1.59, respectively. Conclusion Spectral CT could provide more detailed information for PTMC diagnosis, and it may be useful for PTMC detection in the clinics.关键词
甲状腺微小癌/体层摄影术,X线计算机/能谱CTKey words
Papillary thyroid microcarcinoma/Tomography, X-ray computed/Spectral CT分类
医药卫生
