海南医学院学报2017，Vol.23Issue(2)：152-154,3.DOI:10.13210/j.cnki.jhmu.20161230.015
妊娠期高血压患者子宫动脉及胎儿脐动脉血流动力学研究
Study on uterine artery and fetal umbil ical artery hemodynamics in patients with HDP
摘要
Abstract
[ABSTRACT]Objective:To explore the uterine artery and fetal umbilical artery hemodynamic change in patients with HDP.Methods:A total of 80 patients with HDP who came to our hospital from July,201 5 to July,201 6 for pregnancy exami-nation were included in the study and served as the observation group,while 80 healthy pregnant women who came for preg-nancy examination in the same period were served as the control group.The pregnant women in the two groups were performed with sequential color Doppler ultrasound at gestation 30-40 weeks.The two-dimensional ultrasound apparatus was used to de-tect the uterine artery and umbilical artery.PI,RI,and S/D were recorded.The fetal BPD,head girth,femur length,and ab-dominal girth were measured.ELISA was used to detect 8-iso-PGF2α.The immunoturbidimetry was used to detect Cys-C and CRP.Results:The uterine artery PI,RI,and S/D in the observation group were significantly higher than those in the control group (P <0.05).The umbilical artery PI,RI,and S/D in the observation group were significantly higher than those in the control group (P <0.05).The fetal BPD,head girth,femur length,and abdominal girth in the observation group were signifi-cantly less than those in the control group (P <0.05).8-iso-PGF2α,Cys C,and CRP levels in the observation group were sig-nificantly higher than those in the control group (P <0.05).Conclusions:The uterine artery and umbilical artery blood flow re-sistance in patients with HDP are significantly elevated,which can severely affect the placental blood perfusion and fetal growth and development,while the color Doppler ultrasound can provide a non-invasive diagnosis for fetal distress in uterus.关键词
妊娠高血压/子宫动脉/脐动脉/血流动力学/彩色多谱勒超声Key words
HDP/Uterine artery/Umbilical artery/Hemodynamics/Color Doppler ultrasound分类
医药卫生引用本文复制引用
安景,白睿..妊娠期高血压患者子宫动脉及胎儿脐动脉血流动力学研究[J].海南医学院学报,2017,23(2):152-154,3.基金项目
河北省科学技术成果获奖项目(20120150) （20120150）
