海南医学院学报2017，Vol.23Issue(2)：255-257,261,4.DOI:10.13210/j.cnki.jhmu.20161115.052
甲状腺功能亢进患者骨密度、骨代谢指标及细胞因子的变化研究
Changes of bone mineral density,bone metabol ism indices and cell factors in patients with hyperthyroidism
摘要
Abstract
[ABSTRACT]Objective:To observe the changes of bone mineral density,bone metabolism indices and cell factor in pa-tients with hyperthyroidism Methods:A total of 1 1 6 cases of hyperthyroidism patients from June 201 5 to June 201 6 in our hos-pital were selected as the objects of observation group.Then,120 cases of healthy people were selected as the objects of control group.Thyroid function indexes (TT3,TT4,FT3,FT4,TSH),bone mineral density (BMD),bone metabolism indexes (PTH,BGP,PINP)and cell factors (IL-2,IL-6)in both groups were detected and compared.Results:TT3,TT4,FT3,FT4 in the observation group were significantly higher than that in control group (P <0.05).TSH in the observation group was sig-nificantly lower than that in observation group (P <0.05).BMD,PTH in observation group were significantly lower than that in control group (P <0.05).BGP,PINP in observation group were significantly higher than that in control group (P <0.05). IL-2 in observation group was significantly lower than that in control group.IL-6 in observation group was significantly higher than that in control group (P <0.05 ).Conclusions:Bone mineral density in patients with hyperthyroidism decrease and bone metabolism in patients with hyperthyroidism is active.The significant changes of IL-2 and IL-6 also can be seen.In the clinical, we should enhance the detection of these indexes,so as to take measures to prevent and cure the complications such as osteopo-rosis.关键词
甲状腺功能亢进/骨密度/骨代谢/细胞因子Key words
Hyperthyroidism/Bone mineral density/Bone metabolism indicts/Cell factors分类
医药卫生引用本文复制引用
鲁丹,王晓茜,尹翰林..甲状腺功能亢进患者骨密度、骨代谢指标及细胞因子的变化研究[J].海南医学院学报,2017,23(2):255-257,261,4.基金项目
四川省科技厅资助项目(2015SF0391) （2015SF0391）
