中国实用神经疾病杂志2017，Vol.20Issue(2)：22-24,3.
血清脂蛋白相关磷脂酶 A2与动脉粥样硬化性脑梗死的相关性分析
Correlation analysis of serum lipoprotein associated phospholipase A 2 and atherosclerosis cerebral infarction
王智军 1白蓉1
作者信息
- 1. 郑州大学第一附属医院神经内一科 郑州 450052
- 折叠
摘要
Abstract
Objective To probe the relationship between serum lipoprotein associated phospholipase A 2(Lp-PLA2)and atherosclerosis cerebral infarction by detecting the concentration of Lp-PLA2 ,in order to provide basis for clinical diagnosis and treatment .Method 138 patients with cerebral infarction treated in our hospital were selected as study group .In addition ,84 healthy controls with physical examinations were chosen as control group at the same period .The concentration of serum Lp-PLA2 was measured and general data were recorded in two groups .Meanwhile ,after assessing the occurrence of carotid plaques ,we divided all cases in the two groups into plaque group and non-plaque group .Results The concentration of serum Lp-PLA2 in the study group was(179.24 ± 44.71)ng/ml ,which was obviously higher than(158.04 ± 32.30)ng/ml in the con‐trol group(t= 2.184 ,P= 0.032) .Additionally ,the plaque group with the concentration of (188.57 ± 45.92 )ng/ml showed higher level of serum Lp-PLA2 than the non-plaque group with(153.59 ± 32.68)ng/ml ,and the statistical difference was found (t=3.805 ,P=0.000) .Conclusion Lp-PLA2 ,which may be involved in the occurrence and the rupture of plaques ,was one of important risk factors for atherosclerosis cerebral infarction .So the detection of the concentration of serum Lp-PLA2 can con‐tribute to formulating prevention strategies and providing basis for clinical diagnosis and treatment .关键词
脂蛋白相关磷脂酶A2/动脉粥样硬化性脑梗死Key words
Lipoprotein-associated Phospholipase A2/Atherosclerosis cerebral infarction分类
医药卫生引用本文复制引用
王智军,白蓉..血清脂蛋白相关磷脂酶 A2与动脉粥样硬化性脑梗死的相关性分析[J].中国实用神经疾病杂志,2017,20(2):22-24,3.
