湖南中医药大学学报2017，Vol.37Issue(1)：62-64,3.DOI:10.3969/j.issn.1674-070X.2017.01.016
银翘散加减治疗小儿多发性抽动症的临床研究
Clinical Study of Modified Yinqiao Powder in the Treatment of Tourette's Syndrome
丘婧 1王瑞杰2
作者信息
- 1. 北京市密云区中医医院儿科，北京 101500
- 2. 河南中医药大学第二临床医学院，河南 郑州 450002
- 折叠
摘要
Abstract
Objective To observe the effects of modified Yinqiao powder in the treatment of Tourette's syndrome, and analyze its mechanism. Methods From June 2013 to July 2015, 64 cases with Tourette's syndrome in our hospital were se-lected as study subjects and were randomly divided into the observation group and the control group, 32 cases in each group. The control group was treated with haloperidol while the observation group was additionally treated with Yinqiao powder, and both groups were treated for 3 months. The effective rate of treatment was compared between the two groups, and the degree of tic was evaluated by American Yale Global Tic Severity Scale (YGTSS). The levels of serum trace elements [ferrum (Fe) and zinc (Zn)] were detected by atomic absorption spectrometry, and the serum immunoglobulin (IgE) was detected by enzyme-linked immunosorbent assay (ELISA). The adverse reactions were recorded. Results The effective rate of treatment in the ob-servation group (93.7%) was higher than that in the control group (75.0%) (P<0.05). After treatment, the scores of motor tic and occurrence tic, YGTSS score and IgE level in the observation group were significantly lower while the levels of Fe and Zn were significantly higher than those in the control group (all P<0.05). There was no significant difference in the incidence rate of adverse reactions between two groups (P>0.05). Conclusion Yinqiao powder could treat Tourette's syndrome by regulat-ing levels of serum IgE and trace elements Fe and Zn, with high safety. It is worthy of the clinical popularization.关键词
小儿多发性抽动症/银翘散/综合抽动严重程度量表Key words
Tourette's syndrome/Yinqiao powder/YGTSS分类
医药卫生引用本文复制引用
丘婧,王瑞杰..银翘散加减治疗小儿多发性抽动症的临床研究[J].湖南中医药大学学报,2017,37(1):62-64,3.
