检验医学与临床2017，Vol.14Issue(1)：10-12,3.DOI:10.3969/j.issn.1672-9455.2017.01.004
血培养病原菌分布及耐药性分析
Distribution and drug resistance of pathogenic bacteria in blood culture
摘要
Abstract
Objective To analyze the distribution and drug resistance of pathogenic bacteria in blood culture from January 2015 to January 2016 to provide the basis for guiding clinical rational use of antimicrobial agents .Methods The LABSTAR plus fully automatic blood culture instrument was adopted to conduct the continuous monitoring on blood culture bottles .The positive speci‐mens were timely smeared and switched to cultivation .The bacteria identification and drug resistance analysis were performed by u‐sing the Micro Scan Walk/Away‐40 plus automatic microbial identification and drug susceptibility test analysis system .Results A‐mong 1 570 specimens of blood culture ,8 cases of false positive interference were excluded and 135 strains of pathogenic bacteria were isolated ,the positive rate was 8 .6% ,including 58 strains(42 .96% ) of Gram‐positive bacteria ,72 strains(53 .33% ) of Gram‐negative bacteria and 3 strains(2 .22% ) of fungi .Pathogenic bacteria with high detection rate included Escherichia coli ,coagulase‐negative Staphylococci .Escherichia coli and Klebsiella pneumoniae were sensitive to meropenem ,cefoxitin ,amikacin ,and so on .Co‐agulase‐negative Staphylococci were sensitive to vancomycin and moxifloxacin .Conclusion The kinds of pathogenic bacteria in blood culture of this hospital are complex and drug resistance difference is larger .Monitoring the types and drug resistance of patho‐genic bacteria contributes to rational drug use in clinic and avoid the abuse of antibiotic drugs .关键词
血培养/病原菌/耐药性Key words
blood culture/pathogenic bacteria/drug resistance引用本文复制引用
刘小花,李思雨,陈涛,陈华根,陈宇宁..血培养病原菌分布及耐药性分析[J].检验医学与临床,2017,14(1):10-12,3.基金项目
四川省卫生厅科研课题（130534）；四川省成都市新都区社会事业科技计划项目（2014．07）。 （）
