王强 1唐才喜 1冯斌 1杨凯庆 1贺明连 1赵志坚1
作者信息
- 1. 株洲市中心医院 肝胆胰外科，湖南 株洲 412000
- 折叠
摘要
Abstract
Objective To investigate the clinical effect of early bowel -relaxing treatment and drainage in the treatment of severe acute pan-creatitis (SAP).Methods A retrospective analysis was performed for the clinical data of 52 patients with SAP who were admitted to De-partment of Hepatopancreatobiliary Surgery,Zhuzhou Central Hospital,from January 2009 to January 2015,and these patients were divided into conventional treatment group with 22 patients and early bowel -relaxing/drainage group with 30 patients.The incidence of multiple or-gan dysfunction syndrome and abdominal compartment syndrome within 2 weeks,time to intra -abdominal pressure reduced to below 15 cm H2 O,time to gastrointestinal function recovery,pancreatic infection rate,and mortality rate were compared between the two groups.The in-dependent samples t -test was used for comparison of continuous data between the two groups,and the chi -square test was used for compar-ison of categorical data.Results Compared with the conventional treatment group,the early bowel -relaxing/drainage group had significant reductions in the incidence rates of multiple organ dysfunction syndrome (31.8% vs 10.0%,χ2 =3.89,P =0.049)and abdominal com-partment syndrome (22.7% vs 3.3%,χ2 =4.68,P =0.031)within 2 weeks,pancreatic infection rate (40.9% vs 13.3%,χ2 =5.15,P=0.023),and mortality rate (22.7% vs 3.3%,χ2 =4.68,P =0.031).Compared with the conventional treatment group,the early bowel-relaxing/drainage group had significantly shortened time to intra -abdominal pressure reduced to below 15 cm H2 O,time to bowel sound recovery,and time to the recovery of passing of flatus and defecation (t =1.02,6.67,and 2.13,all P <0.01).Conclusion In the early stage of SAP,bowel -relaxing treatment and drainage can effectively reduce intra -abdominal hypertension,protect vital organ function,al-leviate the condition of SAP,reduce the incidence of complications,and thus significantly improve the prognosis of SAP.关键词
胰腺炎,急性坏死性/引流术/通便/治疗结果Key words
pancreatitis,acute necrotizing/drainage/relaxing bowels/treatment outcome分类
医药卫生
