临床肝胆病杂志2017,Vol.33Issue(1):121-125,5.DOI:10.3969/j.issn.1001-5256.2017.01.026
加速康复外科在胰十二指肠切除术中应用安全性评价的 Meta 分析
Safety of fast track surgery in pancreaticoduodenectomy:a Meta -analysis
摘要
Abstract
Objective To investigate the safety and clinical effect of fast track surgery in pancreaticoduodenectomy,one of the most complex surgeries in general surgery.Methods The Chinese and foreign databases were searched for articles on the application of fast tract surgery in pancreaticoduodenectomy published from January 1994 to April 2016.Two researchers evaluated the quality of the articles which met the inclusion criteria and extracted related data.Stata 12.0 software was used to analyze the overall incidence rate of complications and the inci-dence rates of pancreatic leakage and gastrointestinal emptying disorder,and the Begg rank correlation test and Egger linear regression meth-od were used to investigate publication bias.Results The fast track surgery group had a significantly lower overall incidence rate of compli-cations than the conventional group (RR =0.748,95%CI:0.680 -0.824,P <0.001).There was no significant difference in the inci-dence rate of pancreatic leakage between the two groups (RR =0.894,95%CI:0.734 -1.089,P =0.266).The fast track surgery group had a significantly lower incidence rate of gastrointestinal emptying disorder than the conventional group (RR =0.520,95%CI:0.400 -0. 670,P <0.001).Conclusion Fast track surgery is safe and effective in pancreaticoduodenectomy,but the application of some measures in fast track surgery still needs more medical evidence.关键词
胰十二指肠切除术/加速康复外科/手术后并发症/Meta 分析Key words
pancreaticoduodenectomy/enhanced recovery after surgery/postoperative complications/Meta -analysis分类
医药卫生引用本文复制引用
李伟男,杨刚,李敬东,唐涛,李强,李勇..加速康复外科在胰十二指肠切除术中应用安全性评价的 Meta 分析[J].临床肝胆病杂志,2017,33(1):121-125,5.基金项目
国家自然科学基金(81402444);四川省科技厅项目 ()