临床肝胆病杂志2017，Vol.33Issue(1)：171-174,4.DOI:10.3969/j.issn.1001-5256.2017.01.040
PIVKA－Ⅱ在肝细胞癌诊断及预后判断中的作用
Role of serum abnormal prothrombin protein induced by vitamin K absence or antagonist -Ⅱ in development and progression of hepatocellular carcinoma
摘要
Abstract
Early diagnosis of hepatocellular carcinoma (HCC)using tumor markers is very important for long -term survival.This article e-laborates on the value and high sensitivity and specificity of protein induced by vitamin K absence or antagonist -Ⅱ (PIVKA -Ⅱ)in the early diagnosis,prognostic evaluation,and recurrence prediction of HCC.Its combination with alpha -fetoprotein can significantly increase the early diagnostic rate of HCC.It is pointed out that dynamic measurement of PIVKA -Ⅱ level can assist the correct evaluation of the de-velopment,progression,invasion /metastasis,and recurrence of HCC and can be used as an important marker for the prognosis of HCC.关键词
癌,肝细胞/PIVKA -Ⅱ/综述Key words
carcinoma,hepatocellular/protein induced by vitamin K absence or antagonist Ⅱ/review分类
医药卫生引用本文复制引用
李俊利,尚佳,宁会彬,郭恩恩,何佳..PIVKA－Ⅱ在肝细胞癌诊断及预后判断中的作用[J].临床肝胆病杂志,2017,33(1):171-174,4.基金项目
河南省科技厅基础与前沿技术研究项目 （）
