摘要
Abstract
Objective To investigate clinical characteristics and misdiagnosed causes of pseudomyxoma peritonei ( PMP). Methods Clinical data of 12 misdiagnosed patients with PMP admitted during March 2011 and March 2015 was ret-rospectively analyzed. Results The mainly clinical manifestations of 12 patients were progressive abdominal distention and seroperitoneum by abdominal CT and ultrasound examination,and tuberculosis antibody and tumor markers were positive in some patients. At primary diagnosis,4 patients were misdiagnosed as having abdominal malignant tumor for further examina-tion,3 patients with cirrhosis seroperitoneum,2 patients with ovarian neoplasms,2 patients with tuberculous peritonitis and 1 patient with peritoneal metastatic tumor. Among them,8 patients were misdiagnosed in gastroenterology department,2 patients by gynaecology department and two patients by oncology department. After admitting in our hospital,PMP was confirmed by mucus tissues or columnar epithelium cells which were found by peritoneal biopsy under ultrasound and combination of results of abdominal ultrasound and CT examination. All patients underwent surgery,and PMP was confirmed by postoperative patho-logical results. Intraperitoneal hyperthermic perfusion chemotherapy was performed for 7 patients after operation. With 8-48 months of follow-up,9 patients were found recurrence,among which 4 patients without intraperitoneal hyperthermic perfusion chemotherapy had a recurrence in postoperative 8-16 months. Conclusion PMP is rare,and its clinical manifestations are not typical,and therefore it is difficult to confirm diagnosis. Combined examination of abdominal ultrasound,CT and perito-neal biopsy is helpful for diagnosis. Cytoreduction combined with intraperitoneal hyperthermic perfusion chemotherapy is the main therapy for PMP patients with good short-term prognosis.关键词
腹膜假黏液瘤/误诊/肝硬化/卵巢肿瘤/腹膜炎,结核性/化学疗法,肿瘤,局部灌注Key words
Pseudomyxoma peritonei/Misdiagnosis/Liver cirrhosis/Ovarian neoplasms/Peritonitis,tuberculous/Chemotherapy,cancer,regional perfusion分类
医药卫生
