临床误诊误治2017，Vol.30Issue(1)：21-24,4.DOI:10.3969/j.issn.1002-3429.2017.01.008
容易误诊的孤立性胃十二指肠克罗恩病二例诊疗回顾分析
Retrospective Analysis of 2 Misdiagnosed Patients with Isolated Gastroduodenal Crohn Disease
宁晓燕 1王伟福 1陈晓武 1蔡少薇 1黎丽旋 1王晋涛 1付延玉 1许鸣1
作者信息
- 1. 510317 广州，广东省第二人民医院消化科
- 折叠
摘要
Abstract
Objective To summarize clinical features and experiences of diagnosis and treatment of isolated gastrodu-odenal Crohn disease( CD). Methods Clinical data of 2 isolated gastroduodenal CD patients was retrospectively analyzed. Results The 2 isolated gastroduodenal CD patients were all young male,and the main symptom was gastric outlet obstruc-tion. One patient had accompanied with belly ache and haematemesis,and underwent appendicectomy at 3rd d after onset,and was confirmed gastroduodenal CD on 9 th d after surgery. Another patient had accompanied with weight loss,mild anemia and hypoalbuminemia,and treatment for peptic ulcer was noneffective,and was confirmed gastroduodenal CD in more than 2 months after onset. Gastroscopes examination for the 2 patients showed that hyperemia,edema and multiple ulcers in the stom-ach and/or duodenum mucous membrane,and cobble-like hyperplasia in duodenum mucous membrane. The histopathological examination showed granulation tissues,fissuring ulcers and small abscesses in mucosa and submucosa. Digestive tract radio-graphy and colonoscopy examination showed that there was no ileocolon lesion. Pulse glucocorticoids therapy was performed for the 2 patients after confirming isolated gastroduodenal CD. Symptoms were relieved quickly,and gastroscopy examination showed the lesions had remarkable alleviated in a short time. Conclusion Clinical manifestations of isolated gastroduodenal CD include gastric outlet obstruction,and accompanied with bleeding and malnutrition sometimes,and therefore differential diagnosis with peptic ulcer should be made.关键词
Crohn病/胃疾病/十二指肠疾病/误诊/消化性溃疡Key words
Crohn disease/Stomach diseases/Duodenal diseases/Misdiagnosis/Peptic ulcer分类
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宁晓燕,王伟福,陈晓武,蔡少薇,黎丽旋,王晋涛,付延玉,许鸣..容易误诊的孤立性胃十二指肠克罗恩病二例诊疗回顾分析[J].临床误诊误治,2017,30(1):21-24,4.
