临床误诊误治2017，Vol.30Issue(1)：35-38,4.DOI:10.3969/j.issn.1002-3429.2017.01.012
新型隐球菌性脑膜炎临床特点及误诊分析
Clinical Characteristics and Misdiagnosed Causes of Patients with Cryptococcus Neoformans Meningitis
于利利 1陈永敏 1廖小平 1李其富 1陈志斌 1王淑荣 1马琳1
作者信息
- 1. 570102 海口，海南医学院附属医院神经内科
- 折叠
摘要
Abstract
Objective To investigate clinical characteristics and misdiagnosed causes of cryptococcus neoformans meningitis( CNM)in order to reduce the misdiagnosis rate. Methods Clinical data of 12 misdiagnosed patients with CNM admitted during January 1995 and January 2016 was retrospectively analyzed. Results The first symptoms were headache, dizziness,vomiting and fever mainly. A total of 11 patients were diagnosed and treated in other hospitals. The 8 patients were misdiagnosed,in which 4 patients were misdiagnosed as having upper respiratory tract infection and 3 patients as having tuber-culous meningitis in other hospitals,and 1 patient was misdiagnosed as having bacterial meningitis in our hospital,and misdi-agnosed rate was 75. 00﹪. CNM was confirmed after repeatedly cerebrospinal fluid ink staining and cytopathology examina-tions,and 2 patients were cured,and 10 patients turned for the better after anti-fungal treatment. Conclusion Patients with CNM are mainly young and sporadic type. Clinicians should repeatedly perform cerebrospinal fluid ink staining and cytopathol-ogy examinations to avoid misdiagnosis.关键词
脑膜炎,隐球菌性/误诊/呼吸道感染/结核,脑膜/脑膜炎,细菌性Key words
Meningitis,cryptococcal/Misdiagnosis/Respiratory tract infections/Tuberculosis,meningeal/Menin-gitis,bacterial分类
医药卫生引用本文复制引用
于利利,陈永敏,廖小平,李其富,陈志斌,王淑荣,马琳..新型隐球菌性脑膜炎临床特点及误诊分析[J].临床误诊误治,2017,30(1):35-38,4.
