山东医药2017，Vol.57Issue(2)：25-28,4.DOI:10.3969/j.issn.1002-266X.2017.02.007
糖尿病患者不同体质量指数对高血压发病的影响
Effects of different body mass index in diabetes patients on incidence of hypertension
摘要
Abstract
Objective To explore the relationship between body mass index (BMI)and the new-onset hypertension in diabetic patients.Methods According to the baseline BMI measurement from June 2006 to October 2007,2 367 diabetic patients were divided into the obese group (BMI <28 kg/m2 )and non-obese group (BMI≥28 kg/m2 ),and in accordance with the baseline BMI quartile,they were divided into groups with BMI <23,23-<25,25-<27 and ≥27 kg/m2 .During June 2008 to October 2009,a repeated health examination was carried out to observe the incidence of hypertension in dia-betic patients with different BMI.Multiple Logistic regression analysis was used to test the BMI level and the hypertension. Results ① The incidence rate of hypertension was 38.36% in 2 367 diabetic patients,and the incidence rate in males (40.21%)was higher than that in females (31.03%),(P <0.05).The incidence of hypertension was higher in the obese group (48.91%)than that (35.83%)in the non-obese group(P <0.01).The incidence rates of hypertension in patients with BMI <23,23-<25,25-<27 and ≥27 kg/m2 were 29.83%,36.15%,40.81% and 46.62%,respective-ly,and significant difference was found between them (P <0.01).After the stratification by gender,the incidence rates of hypertension in males were 32.06%,37.45%,43.51% and 47.63%,respectively (P <0.01).The incidence rates of hypertension in females were 22.92%,28.89%,29.57% and 42.97%,respectively (P <0.01).② Univariate analysis showed that the overall risk of hypertension odds ratio (OR)was 1.332,1.622 and 2.055 in patients with BMI 23-<25, 25-<27 and ≥27 kg/m2 as compared with that with BMI <23 kg/m2 .The OR value was 2.534 for females with BMI≥27 kg/m2 ,and 1.632 and 1.927 for males with BMI of 25-27 and ≥27 kg/m2 ,respectively.Multivariate Logistic regression analysis showed that after adjustment for age,systolic blood pressure and other factors,the OR for all and males with BMI of 25-27 kg/m2 were 1.400,1.412,the OR values for all,males and females with BMI≥27 kg/m2 were 1.729,1.596, and 2.636 as compared with those of the patients with BMI <23 kg/m2 .Conclusion BMI may be an risk factor for the new-onset hypertension in diabetic patients,and BMI has a greater impact on the incidence of hypertension in male diabetic patients .关键词
糖尿病/体质量指数/高血压Key words
diabetes mellitus/body mass index/hypertension分类
医药卫生引用本文复制引用
黄玉艳,孙静,陈秀清,田剑,刘晓翠,陈朔华,刘鹏,吴寿岭..糖尿病患者不同体质量指数对高血压发病的影响[J].山东医药,2017,57(2):25-28,4.基金项目
河北省医学科学研究重点课题计划项目（20110632）。 （）
