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应用合成生物学策略改良光合蓝细菌

孙韬 陈磊 张卫文

生物产业技术Issue(1):58-63,6.
生物产业技术Issue(1):58-63,6.DOI:10.3969/j.issn.1674-0319.2017.01.009

应用合成生物学策略改良光合蓝细菌

Engineering of photosynthetic cyanobacteria strains using synthetic biology:a review

孙韬 1陈磊 1张卫文1

作者信息

  • 1. 天津大学化工学院合成微生物学实验室,天津 300072
  • 折叠

摘要

Abstract

Cyanobacteria have emerged as an important chassis for producing biofuels and chemicals due to their capability to directly utilize sunlight and CO2 as the sole energy and carbon sources. Recent progresses in developing and applying various synthetic biology tools have led to the successful constructions of novel pathways of several dozen green fuels and chemicals utilizing cyanobacterial chassis. In recent years, numerous researches have been conducted to enhance the production of green fuels and chemicals through cyanobacterial chassis engineering includ-ing photosynthesis, CO2 uptake and fixation, products exporting, tolerance and cellular regulation. In this article, we critically reviewed recent progresses and universal strategies in cyanobacterial chassis engineering to make it more robust and effective for bio-chemicals production.

关键词

合成生物学/蓝细菌/生物燃料/化学品/菌种改良

Key words

synthetic biology/cyanobacteria/biofuels/bio-chemicals/strain engineering

引用本文复制引用

孙韬,陈磊,张卫文..应用合成生物学策略改良光合蓝细菌[J].生物产业技术,2017,(1):58-63,6.

生物产业技术

1674-0319

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