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产丁醇梭菌基因改造的研究进展

张超 王义强 王启业 黄瑞春 米小琴

生物技术通报2017,Vol.33Issue(1):106-113,8.
生物技术通报2017,Vol.33Issue(1):106-113,8.DOI:10.13560/j.cnki.biotech.bull.1985.2017.01.011

产丁醇梭菌基因改造的研究进展

Research Progress for Genetic Modification of Butanol-producing Clostridia

张超 1王义强 1王启业 1黄瑞春 2米小琴2

作者信息

  • 1. 中南林业科技大学经济林培育与保护教育部重点实验室 中南林业科技大学生物技术实验室,长沙 410004
  • 2. 湘西州森林生态研究实验站,湘西 416000
  • 折叠

摘要

Abstract

Butanol-producing Clostridia as butanol fermentation strains have been studied frequently in recent years. As a new renewable energy sources,butanol has obviously more advantages than ethanol. Therefore,it is of great significance to study gene modification of butanol-producing Clostridia. In this review,from three aspects of key genes,glycolytic pathway,and butanol tolerance,we introduced the latest research progress on gene modification of butanol-producing Clostridia. Meanwhile,we discussed the issues in the current research,and put forward suggestions on how to improve the butanol yield,aiming at providing some new ideas for the researchers.

关键词

产丁醇梭菌/ABE发酵/EMP/基因过表达/基因失活/丁醇耐受性

Key words

butanol-producing Clostridia/ABE fermentation/EMP/gene overexpress/gene inactivation/butanol tolerance

引用本文复制引用

张超,王义强,王启业,黄瑞春,米小琴..产丁醇梭菌基因改造的研究进展[J].生物技术通报,2017,33(1):106-113,8.

基金项目

国家林业局“948”项目 ()

生物技术通报

OA北大核心CSCDCSTPCD

1002-5464

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