中国组织工程研究2017，Vol.21Issue(3)：440-444,5.DOI:10.3969/j.issn.2095-4344.2017.03.021
髓核置换、全椎间盘置换及腰椎后路动态稳定系统治疗腰椎退行性疾病的应用与思考
Application and thinking of nucleus replacement, total disc replacement and posterior lumbar dynamic stabilization device for lumbar degenerative diseases
摘要
Abstract
BACKGROUND:Lumbar fusion surgery as an important and effective means of treating degenerative diseases is widely used in clinical application for almost a century. However, long-term clinical evidence showed that lumbar fusion also brought some problems, such as the loss of waist flexibility, complications of donor site, fusion segment motion loss and accelerating the adjacent segment degeneration. In recent years, the theory of spinal dynamic stabilization had spread widely, and a variety of non-fusion surgery is becoming more broadly used in treatment of lumbar degenerative disease. OBJECTIVE:To review the application of non-fusion surgery in the treatment of lumbar degenerative diseases and explain application perspectives and experiences. METHODS:Databases including PubMed and CNKI were retrieved to col ect clinical application and views about non-fusion internal fixation in the treatment of lumbar degenerative diseases from 2007 to 2016. The key words were“lumbar, non-fusion, bone fusion, dynamic stabilization, adjacent segment degeneration”. RESULTS AND CONCLUSION:Thirty papers were included in the final analysis after screening by two independent researchers. We summarized the lumbar non-fusion technology, including artificial nucleus replacement, total disc replacement and posterior lumbar dynamic stabilization device. The philosophy of these new technologies is to provide stability and physiological activity, reducing the abnormal stress that leads to adjacent segment degeneration. These methods can be applied to the step of treatment of lumbar degenerative diseases and to reduce the fusion of diseased segments. Simultaneously, it is needed to strictly grasp the indications for surgery, to identify the cause of the pain caused by low back pain and lumbar spine instability, and to select the most suitable non-fusion device for individual treatment.关键词
骨科植入物/人工假体/脊柱外科/非融合/植骨融合/内固定/腰椎退行性疾病/相邻节段退变/髓核置换/椎间盘置换/动态稳定/广东省自然科学基金分类
医药卫生引用本文复制引用
刘付仟,梁伟国,叶冬平..髓核置换、全椎间盘置换及腰椎后路动态稳定系统治疗腰椎退行性疾病的应用与思考[J].中国组织工程研究,2017,21(3):440-444,5.基金项目
广东省自然科学基金(2015A030313736)；广东省科技厅项目(2013B021800070) （2015A030313736）
