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非典型缓解性血清阴性对称性滑膜炎伴凹陷性水肿综合征的临床特点

武加标 任敏 赵东宝

新医学2017,Vol.48Issue(1):40-43,4.
新医学2017,Vol.48Issue(1):40-43,4.DOI:10.3969/j.issn.0253-9802.2017.01.009

非典型缓解性血清阴性对称性滑膜炎伴凹陷性水肿综合征的临床特点

Clinical characteristics of atypical remitting seronegative symmetrical synovitis with pitting edema syn-drome

武加标 1任敏 1赵东宝2

作者信息

  • 1. 213002 常州,江苏大学附属武进医院风湿科
  • 2. 200000 上海,上海长海医院风湿免疫科
  • 折叠

摘要

Abstract

Objective To summarize the clinical characteristics of atypical remitting seronegative synovitis with pitting edema syndrome (RS3PE).Methods Clinical data of 10 RS3PE patients were retro-spectively analyzed.Clinical characteristics,treatment and prognosis were reviewed.Results Among 10 ca-ses,the mean age was (67.6 ±14.8)years with a mean duration of 1.70 months.Among them,4 cases are initially diagnosed with elderly onset rheumatoid arthritis,3 initially diagnosed with polymyalgia rheumatic and the remaining 3 with spinal arthritis,undifferentiated arthritis and gout.Two patients presented with no recur-rence after treatment with a small dose of glucocorticoids (hormone),and 8 cases were treated with hormone therapy combined with anti-rheumatic drugs,and clinical symptoms were alleviated.All patients were followed up for 12-18 months.A middle-aged patient presented with tuberculosis meningitis at 13 months after treat-ment.Conclusions Clinical symptoms of atypical RS3PE patients are rarely seen.It is likely to be misdiag-nosed as elderly onset rheumatoid arthritis and polymyalgia rheumatic.Atypical RS3PE is sensitive to a small dose of hormone therapy.Anti-rheumatic drugs should be supplemented.Patients with poor response to clinical treatment should be closely monitored.

关键词

缓解性血清阴性对称性滑膜炎伴凹陷性水肿综合征/风湿性多肌痛/类风湿关节炎/老年起病

Key words

Remitting seronegative symmetrical synovitis with pitting edema syndrome/Polymyalgia rheumatica/Rheumatoid arthritis/Elderly onset

引用本文复制引用

武加标,任敏,赵东宝..非典型缓解性血清阴性对称性滑膜炎伴凹陷性水肿综合征的临床特点[J].新医学,2017,48(1):40-43,4.

基金项目

常州市武进区科技支撑计划项目 ()

新医学

OACSTPCD

0253-9802

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