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磁悬浮植入式心室辅助装置体外水力学及溶血实验

吴广辉 蔺嫦燕 徐创业 刘修健 何玉娜 杨朋 陈琛

中国医疗设备2017,Vol.32Issue(1):14-17,4.
中国医疗设备2017,Vol.32Issue(1):14-17,4.DOI:10.3969/j.issn.1674-1633.2017.01.004

磁悬浮植入式心室辅助装置体外水力学及溶血实验

Hydraulics and in Vitro Hemolysis Test of Implantable Magnetic Suspending Ventricular Assist Device

吴广辉 1蔺嫦燕 1徐创业 1刘修健 1何玉娜 1杨朋 2陈琛2

作者信息

  • 1. 首都医科大学附属北京安贞医院北京市心肺血管疾病研究所生物医学工程研究室,北京100029
  • 2. 苏州同心医疗器械有限公司 研发部,江苏 苏州 215125
  • 折叠

摘要

Abstract

Objective To test the working performance and hemocompatibility of a small implantable magnetic suspending ventricular assist device.Methods The hydraulic pump performance has been tested through in vitro mock circulation loop experiments. The in vitro tests referring to ASTM F1841 standard were made to test the in vitro hemolytic performance.Results It turned out that the pump can deliver 5 L/min for pressures of 100 mmHg at a rotational speed of approximately 3500 rpm. The average normalized index of hemolysis values of the device was (0.0007±0.0003) mg/dL.Conclusion The in vitro hydraulics test indicated that the device works with stable performance and can meet the requirements of adult ventricular assist, meanwhile, it has good hemolytic performance.

关键词

心力衰竭/心室辅助装置/磁悬浮/水力学实验/溶血实验

Key words

heart failure/ventricular assist device/maglev/hydraulics test/hemolysis test

分类

医药卫生

引用本文复制引用

吴广辉,蔺嫦燕,徐创业,刘修健,何玉娜,杨朋,陈琛..磁悬浮植入式心室辅助装置体外水力学及溶血实验[J].中国医疗设备,2017,32(1):14-17,4.

基金项目

国家高技术研究发展计划(863计划)(2012AA041605);国家自然科学基金(81670371)。 ()

中国医疗设备

OACSTPCD

1674-1633

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