医学信息2017，Vol.30Issue(2)：111-113,3.
阿司匹林预防膝关节置换术后下肢深静脉血栓的疗效和安全性
Efficacy and Safety of Aspirin in Prevention of DVT of Lower Limbs after Total Knee Arthroplsaty
刘泽朋 1荣绍远 1李春洪 1李建华 1李玉军2
作者信息
- 1. 北京市昌平区医院骨科，北京 102200
- 2. 北京市西城区积水潭医院矫形骨科，北京 100035
- 折叠
摘要
Abstract
Objective To compare the efficacy and safety of aspirin in prophylaxis of deep venous thrombosis of lower limbs after total knee arthroplasty. Methods From February 2015 to August 2015,120 patients met with our inclusion criteria.All the patients were divided into 2 groups randomly. One group received aspirin enteric-coated tablets 150mg/day since the first day after operation till discharge14 days, and other group received subcutaneous injection of low molecular weight heparin (LMWH) with 2500 Axa IU once daily for 14 days. Estimate the efficacy and safety of aspirin in prevention of DVT of lower limbs after total knee arthroplsaty. Results 4 patients (6.7%) were diagnosed with deep venous thrombosis in group Aspirin. In group LMWH ,3patients (5.0%)had DVT. There were no symptomatic and suspicious pulmonary embolism in two groups. There were no statistic significances between the two groups in all these aspects,such as the quantity of bleeding、decrease of hemoglobin、hematoma rate and infection rate. Conclusion Contrast Aspirin and LMWH, there is no difference in venous thromboemlolism prophylaxis、blood lost and hemorrhage complication postoperation. But Aspirin is cheap, drug-nature stable, administered orally, well tolerated, as a partion of multimodality anticoagulant therapy after total knee arthroplasty.关键词
关节成形术/膝关节/下肢深静脉血栓形式/阿司匹林Key words
Arthroplasty/Knee joint/Venous thrombosis/Aspirin引用本文复制引用
刘泽朋,荣绍远,李春洪,李建华,李玉军..阿司匹林预防膝关节置换术后下肢深静脉血栓的疗效和安全性[J].医学信息,2017,30(2):111-113,3.
