中国免疫学杂志2017，Vol.33Issue(1)：108-111,4.DOI:10.3969/j.issn.1000-484X.2017.01.022
RhoGDI2在结直肠癌中的表达及临床意义
RhoGDI2 expression and clinical significance in colorectal cancer
摘要
Abstract
Objective:To explore the expression and clinical significance of RhoGDI2 in colorectal cancer. Methods:Immuno-histochemistry was used to identify RhoGDI2 expression in clinical samples of colorectal cancer tissues,para-tumorous tissues and lymph node metastasis tissues. The relationships between CRC clinical factors and survival were analyzed. Results: RhoGDI2 expression contributed positively with tumor progression and metastasis in clinical tissues. It was associated with the stage of the tumor,lymph node metastasis, remote metastasis, venous invasion and vessel invasion. Patients with higher RhoGDI2 expression had poorer overall survival. Conclusion:RhoGDI2 showed high expression in colorectal cancer and it was associated with the stage of the tumor,lymph node metastasis,remote metastasis, venous invasion and vessel invasion. Patients with higher RhoGDI2 expression had poorer overall survival.关键词
RhoGDI2/结直肠癌/转移Key words
RhoGDI2/Colorectal cancer/Metastasis分类
医药卫生引用本文复制引用
柳思琪,马俐君,颜宏利,王文睿,金珍婧..RhoGDI2在结直肠癌中的表达及临床意义[J].中国免疫学杂志,2017,33(1):108-111,4.基金项目
本文受吉林省发展和改革委员会资助(2013C026-1)。 （2013C026-1）
