中国全科医学2017，Vol.20Issue(2)：214-218,5.DOI:10.3969/j.issn.1007-9572.2017.02.019
甲状腺功能亢进症患者中桥本甲状腺炎的比例及其生化和病理特征
The Proportion,Biochemical and Pathological Characteristics of Hashimoto's Thyroiditis in Hyperthyroidism
何珂 1胡源 1朱丽华 1陆西宛 1毛晓明2
作者信息
- 1. 214000 江苏省无锡市中医医院 南京中医药大学无锡附属医院内分泌科
- 2. 210001 江苏省南京市第一医院 南京医科大学附属南京医院内分泌科
- 折叠
摘要
Abstract
Objective To investigate the proportion of histopathologically confirmed Hashimoto's thyroiditis(HT)in clinically diagnosed Graves' disease ( GD) patients with hyperthyroidism,and evaluate the biochemical and pathological characteristics. Methods From 2012 to 2014,thirty - six patients with hyperthyroidism who were clinically diagnosed as GD in the Department of Endocrinology and Thyroid - breast Surgery at Nanjing First Hospital accepted thyroidectomy. The thyroid tissues accepted routinely pathological examination after the surgery. The proportions of GD,HT,and GD + HT were calculated and the biochemical and pathological features were analyzed. Results In all 36 patients with hyperthyroidism,26(72. 2% )of them were GD confirmed by histopathology,7(19. 5% )were HT,and 3(8. 3% )were GD + HT. There were no statistically significant differences in gender,age,course of disease,TSH,FT3 ,FT4 and TRAb level among the three groups( P >0. 05). There were statistically significant differences in TPOAb and TGAb level among the three groups( P < 0. 05). The TPOAb level in GD + HT group was higher than that in GD group,and TGAb level in HT group and GD + HT group were higher than that in GD group(P < 0. 05). Conclusion HT accounted for a certain proportion in hyperthyroidism. HT and GD + HT might be the different stages in the development from GD to HT.关键词
格雷夫斯病/桥本病/甲状腺功能亢进症Key words
Graves disease/Hashimoto disease/Hyperthyroidism分类
医药卫生引用本文复制引用
何珂,胡源,朱丽华,陆西宛,毛晓明..甲状腺功能亢进症患者中桥本甲状腺炎的比例及其生化和病理特征[J].中国全科医学,2017,20(2):214-218,5.
