中国全科医学2017，Vol.20Issue(5)：579-585,7.DOI:10.3969/j.issn.1007-9572.2017.05.015
上海市社区2型糖尿病患者糖尿病周围神经病变现况调查
Existing Circumstances Research of Diabetic Peripheral Neuropathy of Type 2 Diabetes Mellitus Patients Based on Community Population in Shanghai
摘要
Abstract
Objective To investigate the prevalence of diabetic peripheral neuropathy(DPN)of patients with type 2 diabetes mellitus in Shanghai community and its influencing factors. Methods With cluster random sampling method,5 053 patients with type 2 diabetes mellitus of six communities in Pudong New Area and Yangpu District in Shanghai accepted questionnaires survey,physical examination and laboratory tests from October 2014 to April 2015,DPN was screened by Toronto Clinical Scoring Scale(TCSS),and divided into nonexistent DPN,mild DPN,moderate DPN,and severe DPN. Multivariate Logistic regression analysis was used to analyze the influence factors of developing DPN. Results The positive rate of DPN screening was 16. 0% (810 / 5 053),of which 612(12. 1% ) were mild DPN,158(3. 1% ) were moderate DPN,and 40 (0. 8% )were severe DPN. There were no significant differences in the prevalence of DPN among subjects of different gender, subjects with or without abdominal obesity and subjects smoking or not( P > 0. 05);there were significant differences in the prevalence of DPN among subjects with different ages,disease durations,body mass index(BMI)(P < 0. 001). There were no significant differences in the prevalence of DPN among subjects of different FPG levels and subjects combined with or without hypertension(P > 0. 05);there were significant differences in the prevalence of DPN among subjects of different levels of 2 -hour postprandial blood glucose(2 hPG),glycosylated hemoglobin( HbA1c ),low density lipoprotein cholesterin( LDL-C), high density lipoprotein cholesterol( HDL-C),urinary albumin to creatinine ratio( ACR) and different severity degree of diabetic retinopathy(DR)(P < 0. 05). Multivariate Logistic regression analysis showed that age≥65,disease duration≥15 years,HbA1c≥8. 5% ,HDL-C≤0. 9 mmol/ L,combining with moderate or severe DR were the risk factors of type 2 diabetes mellitus patients′ DPN being positive(P < 0. 05). Conclusion The prevalence rate of DPN is low in type 2 diabetes mellitus patients in Shanghai community,and mild lesions are the main manifestation. Age≥65,disease duration≥15 years,HbA1c≥8. 5% ,HDL-C≤0. 9 mmol/ L,combining with moderate or severe DR are the risk factors of DPN in type 2 diabetes mellitus patients in community.关键词
糖尿病,2 型/糖尿病神经病变/患病率/筛查/影响因素分析Key words
Diabetes,type 2/Diabetic neuropathies/Prevalence/Screening/Root cause analysis分类
医药卫生引用本文复制引用
杨辉,宋道平,蒋玉立,顾文娟,彭云,程慧琴,秦飞,施榕,朱静芬,贾丽丽,娄洁琼,龙雯,冯易,梁辰,张胜冰..上海市社区2型糖尿病患者糖尿病周围神经病变现况调查[J].中国全科医学,2017,20(5):579-585,7.基金项目
上海市公共卫生重点学科（全科医学）建设项目 （）
