摘要
Abstract
Objective To investigate the application value of content of hemoglobin in reticulocyte( CHr)on the diagnosis iron - deficiency without anemia and iron - deficiency anemia of women during pregnancy. Methods One hundred and nine pregnant women whose pregnancy test were made in Department of Obstetrical,Chinese People′s Liberation Army No. 202 Hospital from November 2015 to March 2016 were selected. According to the levels of hemoglobin( Hb) and serum ferritin (SF),the women were divided into iron - deficiency without anemia group(34 cases),iron - deficiency anemia group(35 cases)and normal pregnant women group(40 cases). Blood analysis indicators in each group was detected,including the mean corpuscular volume(MCV),the mean corpuscular hemoglobin(MCH),the mean corpuscular hemoglobin concentration (MCHC)and CHr. The ROC curves of iron - deficiency without anemia and iron - deficiency anemia diagnosed by indicators in each blood analysis were drawn,and the diagnostic sensitivity and specificity of each blood analysis indicators were got. Results There were significant differences in Hb,SF,MCV,MCH,MCHC and CHr among iron - deficiency without anemia group, iron - deficiency anemia group and normal pregnant women group(P < 0. 001);and the above indicators in iron - deficiency without anemia group and iron - deficiency anemia group were significantly lower than those in normal pregnant women group(P< 0. 05). The areas under ROC curve of MCV,MCH,MCHC and CHr for diagnosis iron - deficiency without anemia were 0. 751,0. 725,0. 720 and 0. 874 respectively;the areas under ROC curve of MCV,MCH,MCHC and CHr for diagnosis iron- deficiency anemia were 0. 965,0. 966,0. 967 and 0. 961 respectively. When the cut - off value of CHr was 29. 0 pg,the sensitivity and specificity for diagnosing iron - deficiency without anemia were 73. 5% and 90. 0% respectively;while the sensitivity and specificity for diagnosing iron - deficiency anemia were 91. 4% and 90. 0% respectively. Conclusion The diagnostic effects of CHr on iron deficiency in pregnant women,especially the condition without anemia and simple iron -deficiency which is easily missed are better. CHr is a sensitive indicator of screening and early diagnosing iron - deficiency in clinic.关键词
贫血,缺铁性/铁缺乏/网织红细胞血红蛋白含量/孕妇/诊断Key words
Anemia, iron - deficiency/Iron deficiency/Reticulocyte hemoglobin concent/Pregnancy women/Diagnosis分类
医药卫生
