中国社区医师2017，Vol.33Issue(3)：21-23,3.DOI:10.3969/j.issn.1007-614x.2017.3.11
右美托咪定在重型颅脑损伤术后患者治疗中的疗效分析
Curative effect analysis of dexmedetomidine in the treatment of severe traumatic brain injury after operation
张磊 1陈汉明 1张友华1
作者信息
- 1. 545006广西柳州市人民医院重症医学科
- 折叠
摘要
Abstract
Objective:To explore the clinical effect of dexmedetomidine in the treatment of severe traumatic brain injury after operation.Methods:54 patients with severe traumatic brain injury were randomly divided into the dexmedetomidine group and the midazolam group with 27 cases in each.They were given postoperative sedation.The intracranial pressure level,time required to reach the target sedation depth,recovery time after drug withdrawal,mechanical ventilation time,ICU hospitalization time and adverse reaction rate were compared between groups.Results:Compared with midazolam,the dexmedetomidine could reduce the intracranial pressure,shorten the time required to reach the target sedation depth,recovery time after drug withdrawal,mechanical ventilation time and ICU hospitalization time,reduce the incidence rate of delirium,but the incidence rate of hypotension and bradycardia were higher(P<0.05).Conclusion:Dexmedetomidine in the patients with severe traumatic brain injury after operation has satisfactory curative effect,better control the intracranial pressure,more easy to wake up,shorten the mechanical ventilation time and ICU hospitalization time,and the incidence rate of delirium is low,but during the course of medication should closely monitor blood pressure and heart rate.关键词
右美托咪定/咪达唑仑/重型颅脑损伤/镇静Key words
Dexmedetomidine/Midazolam/Severe traumatic brain injury/Sedation引用本文复制引用
张磊,陈汉明,张友华..右美托咪定在重型颅脑损伤术后患者治疗中的疗效分析[J].中国社区医师,2017,33(3):21-23,3.
