中国药理学通报2017，Vol.33Issue(1)：14-17,18,5.DOI:10.3969/j.issn.1001-1978.2017.01.003
Wnt信号通路在肿瘤调控方面的研究进展
Research progress on role of Wnt signaling pathway in regulation of tumors
摘要
Abstract
Wnt signaling pathway is a highly conservative signal pathway controlling cell growth,differentiation,apoptosis and self-renewal.This signal pathway is often abnormally activated in tumor development and progression,which can cooperate or antagonize with other signal pathways to regulate tumor prolifera-tion,migration and invasion.This paper makes a review of the recent research of Wnt signaling pathway progression and its function in tumor growth regulation.关键词
Wnt信号通路/β-catenin/APC蛋白/信号通路的调节/机制/肿瘤Key words
Wnt signaling pathway/β-catenin/Adenomatous polyposis coli protein/regulation of signaling pathway/mecha-nism/tumor引用本文复制引用
张世苹,张旭..Wnt信号通路在肿瘤调控方面的研究进展[J].中国药理学通报,2017,33(1):14-17,18,5.基金项目
江苏省2015年度普通高校研究生科研创新计划项目（No KYZZ15-0274）；The People Programme （Marie Curie Ac-tions） of the European Union ’s Seventh Framework Pro-gramme FP7／2007-2013／under REA grant agreement n°PIR SES-GA -2013-612589）；江苏省优势学科和江苏省自然科学基金项目（No BK20131415）；国家自然科学基金资助项目 （）
