中国药理学通报2017，Vol.33Issue(1)：18-21,22,5.DOI:10.3969/j.issn.1001-1978.2017.01.004
胆酸盐外排泵研究的最新进展
The research progress of bile acid efflux pump (BSEP)
摘要
Abstract
Bile acid efflux pump(BSEP)is the major transporter of bile salts secreted by liver cells into the bile,the variation and inhibition of which are connected with cholestasis and drug-induced liver injury.A deep understanding of the physiological and pathological function of BSEP IS achieved by analysis and summary of diseases.The paper briefly illustrates the structure, expression,regulation,substrates,inhibitors and diseases of BSEP,in order to provide further theoretical and experimental basis for the clinical treatment.关键词
胆酸盐外排泵/胆汁淤积/抑制剂/调控/胆汁酸/调节因子Key words
BSEP/cholestasis/inhibitor/regulation/bile acid/regulatory factor引用本文复制引用
赵晶,陈曼玉,李磊..胆酸盐外排泵研究的最新进展[J].中国药理学通报,2017,33(1):18-21,22,5.基金项目
国家自然科学基金资助项目 （）
