中国医学创新2016，Vol.13Issue(36)：11-13,14,4.DOI:10.3969/j.issn.1674-4985.2016.36.003
丙酸氟替卡松气雾剂治疗支气管哮喘患儿的效果及其对血清皮质醇水平的影响分析
Analysis of Clinical Effect of Fluticasone Propionate Aerosol in Treatment of Children with Bronchial ;Asthma and Its Influence on the Serum Cortisol Level
摘要
Abstract
Objective:To explore the effect of Fluticasone Propionate Aerosol in children with bronchial asthma treatment,and analyze its influence on the serum cortisol level.Method:124 children with bronchial asthma and who accepted treatments in our hospital from May 2014 to September 2015 were randomly selected as the observation group,and 120 cases of children’s health examination in our hospital in this period were selected as the control group.Then,the effect of Fluticasone Propionate Aerosol in treatment of children with asthma were discussed,and the influence on the serum cortisol level were discussed by the means of the control study.Result:In the observation group,the serum cortisol level showed slightly decreasing trend in the course of treatment,but there were no differences between each time period compared with the control group(P>0.05), and after treatment for 12 months in the observation group were compared with before treatment and after treatment 6 months,there were no statistically significant differences(P>0.05),the observation group total effective rate was 93.55%(116/124).In the observation group,the level of PEF and FEV1 after treatment 12 months were significantly higher than those before treatment(P<0.05).In the observation group,the daytime and nighttime symptom scores after treatment 12 months were decreased,and which were lower than those before treatment (P<0.05).Conclusion:The application of Fluticasone Propionate Aerosol asthma treatment,clinical efficacy can be achieved ideal,and does not affect the serum cortisol levels in children,with a high clinical value.关键词
支气管哮喘/丙酸氟替卡松气雾剂/血清皮质醇/疗效Key words
Bronchial asthma/Fluticasone Propionate Aerosol/Cortisol/Clinical effect引用本文复制引用
方小桂,刘前程..丙酸氟替卡松气雾剂治疗支气管哮喘患儿的效果及其对血清皮质醇水平的影响分析[J].中国医学创新,2016,13(36):11-13,14,4.基金项目
湖北省卫生厅重大项目 （）
