中国医学创新2016，Vol.13Issue(36)：21-24,25,5.DOI:10.3969/j.issn.1674-4985.2016.36.006
直肠指检与前列腺穿刺活检结果相关指标关系的研究
Study on the Relationship between Digital Rectal Examination and Prostate Biopsy Results
摘要
Abstract
Objective:To explore the relationship between digital rectal examination(DRE)and prostate biopsy results,and to re-evaluate the significance and necessity of DRE. Method:Patients who had prostate biopsy in the Second Hospital of Tianjin Medical University were included in this study,the results of DRE and prostate biopsy were statistically analyzed.The ages,PSA,prostate volume(PV),f/t PSA,PSA density(PSAD)were investigated,the Gleason scores,ECT bone scan results,local neural invasion results of prostate cancer(PCa) patients were collected meanwhile.The relationship between DRE and other results were analyzed.Result:A total of 457 patients were included in the study,223 patients were diagnosed as PCa and 234 patients got negative results in the biopsy,99 patients got positive DRE results,358 patients got negative DRE results. The results of DRE in patients with benign and malignant were compared,the difference was statistically significant(P<0.001). Gleason score,bone metastasis,PSA,PSAD,positive needle number accounting of DRE positive and negative patients were compared,the differences were statistically significant(P=0.045,P=0.044,P<0.001,P<0.001, P=0.021).And for the age,f/t PSA,PV,local neural invasion of the two groups,the differences were not statistically significant(P=0.772,0.316,0.322,0.521).Conclusion:Digital rectal examination is still an important means of screening for prostate cancer,there is a significant correlation between the positive and the degree of malignancy of prostate cancer.While clinicians rely on other advanced inspection,the traditional DRE should also be kept attention at the same time.关键词
前列腺穿刺/直肠指检/前列腺癌/前列腺特异性抗原/Gleason评分Key words
Prostate biopsy/Digital rectal examination/Prostate cancer/Prostate specific antigen/Gleason score引用本文复制引用
张一然,潘盼,连振鹏,郑小康,刘冉录,徐勇..直肠指检与前列腺穿刺活检结果相关指标关系的研究[J].中国医学创新,2016,13(36):21-24,25,5.基金项目
天津市自然科学基金重点项目（15JCZDJC35900）；天津市卫生局重点攻关项目 （）
