中国医学创新2016，Vol.13Issue(36)：133-136,4.DOI:10.3969/j.issn.1674-4985.2016.36.039
白介素-31与特应性皮炎的相关性研究进展
Recent Research Progress of the Correlations between Interleukin-31 and Atopic Dermatitis
焦春秀 1赵鋆 2刘桂芬3
作者信息
- 1. 上海中医药大学 上海 201203
- 2. 上海市松江区妇幼保健院
- 3. 上海中医药大学附属曙光医院
- 折叠
摘要
Abstract
Interleukin-31(IL-31)is a newly discovered cytokine associated with chronic skin inflammation and pruritus.Patients with atopic dermatitis,chronic spontaneous urticaria,allergic contact dermatitis,prurigo nodularis,primary cutaneous lymphoma and mastocytosis exhibit increased serum levels of IL-31 protein and elevated IL-31 mRNA in the skin.And,IL-31 serum levels have been reported to be correlate with disease activity in atopic dermatitis.In the present review,we particularly focus on studies investigating the role of IL-31 in atopic dermatitis.We conclude that growing knowledge about IL-31,its receptors and signaling pathways serve to better understand the pathogenesis of atopic dermatitis and may lead to the development of novel treatment approaches.关键词
特应性皮炎/湿疹/白介素-31/瘙痒Key words
Atopic dermatitis/Interleukin-31/Eczema/Pruritus引用本文复制引用
焦春秀,赵鋆,刘桂芬..白介素-31与特应性皮炎的相关性研究进展[J].中国医学创新,2016,13(36):133-136,4.
