中国医学前沿杂志（电子版）2016，Vol.8Issue(12)：75-78,4.DOI:10.12037/YXQY.2016.12-17
高危型人乳头状瘤病毒DNA检测与液基薄层细胞学检查在宫颈癌癌前病变中的诊断价值比较
Diagnostic value of high risk human papilloma virus DNA and thinprep cytology test in the diagnosis of precancerous lesion of uterine cervical carcinoma
于淼淼 1杨露1
作者信息
- 1. 南京军区总医院 妇产科，南京 210002
- 折叠
摘要
Abstract
Objective To compare the diagnostic value of high risk human papilloma virus (HR-HPV) DNA and thinprep cytology test (TCT) in the diagnosis of precancerous lesion of uterine cervical carcinoma. Method 1195 cases with cervical disease in our hospital from December 2013 to December 2015 were selected and applied with HR-HPV DNA test and TCT. Two kinds of joint detection method were designed, which were COM1(HR-HPV DNA test→TCT) and COM2 (TCT→HR-HPV DNA test). Compared these testing results with the pathological biopsy results and calculated the diagnostic performance of various detection method. Result In the four kinds of detection method, HR-HPV DNA test had higher sensitivity than TCT and COM2 (P<0.05). There was no significant difference of sensitivity between HR-HPV DNA test and COM1 (P>0.05). HR-HPV DNA test had the lowest specificity and diagnose accordance rate (P<0.05). COM1 had the highest specificity and diagnose accordance rate (P<0.05). Conclusion HR-HPV DNA test and TCT have different advantages in the diagnosis of early uterine cervical carcinoma. HR-HPV DNA test firstly and applied TCT further for the patients with positive result of HR-HPV DNA test has better diagnostic efficiency in the diagnosis of early cervical cancer.关键词
人乳头状瘤病毒/液基薄层细胞学检查/宫颈癌/癌前病变Key words
Human papilloma virus/Thinprep cytology test/Uterine cervical carcinoma/Precancerous lesion引用本文复制引用
于淼淼,杨露..高危型人乳头状瘤病毒DNA检测与液基薄层细胞学检查在宫颈癌癌前病变中的诊断价值比较[J].中国医学前沿杂志（电子版）,2016,8(12):75-78,4.
