中国医学装备2017，Vol.14Issue(1)：74-78,5.DOI:10.3969/J.ISSN.1672-8270.2017.01.023
超声造影联合弹性成像在TI-RADS 4类甲状腺结节良恶性鉴别诊断中的应用价值研究
A research of application value for contrast-enhanced ultrasound combined with acoustic elastography on the differential diagnosis benign or malignant thyroid nodules of TI-RADS 4 lesions
商宁 1杜辉 2李军 2史娜 2张素燕 2赵斗贵 3赵红伟4
作者信息
- 1. 邯郸市传染病医院功能科 河北 邯郸 056002
- 2. 邯郸市传染病医院肝病科 河北 邯郸 056002
- 3. 邯郸市传染病医院 河北 邯郸 056002
- 4. 解放军第302医院超声科 北京 100039
- 折叠
摘要
Abstract
Objective:To investigate the value of contrast-enhanced ultrasound(CEUS) combined with acoustic elastography (AE) in differential diagnosis benign or malignant thyroid nodules of TI-RADS 4 lesions.Methods: A retrospective analysis for 132 patients with nodules of TI-RADS 4 lesions was adopted to finish this work. The 132 patients were divided into benign group (50 cases) and malignant group (82 cases). Both of groups were analyzed by CEUS, AE and combination of the two methods, respectively. The pathological findings were set as gold standard. To compare the sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and accuracy between the three methods.Results: Uniform enhancement, ring enhancement, inhomogeneous enhancement, no enhancement and time intensity curve of CEUS in benign group were significantly different with those in nodules group (P<0.05). Grade 4 scores of AE were significantly different between benign group and nodules group (Z=46.73, P<0.05). The sensitivity, specificity, PPV, NPV, and accuracy were 92.68%, 94.55%, 96.20%, 89.66%, 93.43% , respectively, for CEUS combined with AE. The combination of two methods had the highest diagnostic efficacy. Conclusions: CEUS and AE have positive significance for the diagnosis of benign and malignant thyroid nodules in TI-RADS 4. CEUS combined with AE can be further improved in diagnosis accuracy.关键词
超声造影/超声弹性成像/甲状腺结节Key words
Contrast-enhanced ultrasound/Acoustic elastography/Thyroid nodule分类
医药卫生引用本文复制引用
商宁,杜辉,李军,史娜,张素燕,赵斗贵,赵红伟..超声造影联合弹性成像在TI-RADS 4类甲状腺结节良恶性鉴别诊断中的应用价值研究[J].中国医学装备,2017,14(1):74-78,5.
