中国医药科学2016，Vol.6Issue(21)：13-17,5.
失代偿期肝硬化患者肝静脉压力梯度与超声造影参数的相关性分析
Correlation analysis of hepatic vein pressure gradient and contrast-enhanced ultrasonography parameters in patients with decompensated liver cirrhosis
屈保进 1侯秀敏 2费素娟 1李莉 1朱祖安1
作者信息
- 1. 徐州医科大学附属医院消化科，江苏徐州221006
- 2. 徐州医科大学附属医院超声科，江苏徐州221006
- 折叠
摘要
Abstract
Objective To investigate the correlation of hepatic vein pressure gradient and contrast-enhanced ultrasonography parameters in patients, and to explore a new noninvasive evaluation in patients with decompensated liver cirrhosis portal vein pressure. Methods 89 cases of decompensated liver cirrhosis patients in our hospital gastroenterology dept from October 2014 to October 2015 were selected as object of study.All patients HVPG determination and collected the dynamic of contrast-enhanced ultrasound.Three areas of interest of hepatic vein,hepatic artery, portal vein were selected to analyze,and PV-HVTT (Portal vein to hepatic vein transit time)and HA-HVTT(Hepatic artery to hepatic vein transit time) were calculated.Ultrasonic imaging parameters and HVPG were analyzed the correlation by Pearson and ROC curve. Results There were negative correlations between HVAT, PV-HVTT, HA-HVTT and HVPG.ROC curve analysis results showed: PV-HVTT≤2s could predict the sensibility was 0.64,the specificity was 0.81 of HVPG≥12 mmHg of decompensated period liver cirrhosis patients,neverthelessPV-HVTT≤3s could predict the sensibility was 0.77 and the specificity was 0.78 of HVPG≥16 mmHg. Conclusion Contrast-enhanced ultrasonography is a noninvasive,safe,radiationless means of diagnosis. PV-HVTT and HVPG have relativity.It can be used to predict patients with decompensated cirrhosis esophageal gastric varices bleeding.关键词
失代偿期/肝硬化/肝静脉压力梯度/超声造影Key words
Decompensated period/Liver cirrhosis/Hepatic vein pressure gradient/Contrast-enhanced ultrasonography分类
医药卫生引用本文复制引用
屈保进,侯秀敏,费素娟,李莉,朱祖安..失代偿期肝硬化患者肝静脉压力梯度与超声造影参数的相关性分析[J].中国医药科学,2016,6(21):13-17,5.
