中国卒中杂志2017，Vol.27Issue(1)：18-22,5.DOI:10.3969/j.issn.1673-5765.2017.01.003
非痴呆性血管性认知障碍的影响因素研究
The Study on Inlfuencing Factors of Vascular Cognitive Impairment no Dementia
马洪颖 1李瑜霞 1李永秋 1刘春芹 1张冬森 1王丽英 1高轩 1高海凤 1付子娟1
作者信息
- 1. 063000 唐山唐山市工人医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the influencing factors of vascular cognitive impairment no dementia (VCIND). Methods Patients with VCIND in Tangshan Gongren Hospital from January 2014 to January 2016 were recruited into the study group and patients with no cognitive impairment were enrolled into the control group. The differences of vascular risk factors, laboratory data and thyroid hormone were compared between two groups. Logistic regression analysis was used to analyze the independent risk factor. Results There were 115 cases in the study group with VCIND and 147 in the control group. The proportion of hypertension (73.9%vs 53.1%,P=0.001), history of stroke (60.9%vs 34.7%, P<0.001) in the VCIND group was signiifcantly higher than that in the control group. The level of fasting blood glucose (Glu)(P<0.001), homocysteine (Hcy)(P<0.001) and triglyceride (P=0.022) in the VCIND group were signiifcantly higher than that of the control group. The free triiodothyronine (FT3) in the VCIND group was proved lower than that in the control group ([2.80±0.39] pg/mlvs [2.90±0.27] pg/ml,P=0.043]. Multivariate Logistic regression analysis showed: history of stroke (odds ratio[OR] 6.461, 95% confidence interval [CI] 2.835-14.725,P<0.001), Hcy [OR 15.726, 95%CI 7.198-34.358,P<0.001], blood Glu [OR 1.864, 95%CI 1.367-2.541,P<0.001] were independent risk factors of VCIND, and FT3 [OR 0.351, 95%CI 0.192-0.647,P<0.001] were the protective factors of VCIND. Conclusion History of stroke, Hcy and high blood Glu level are independent risk factors of VCIND, while FT3 is the protective factor of VCIND.关键词
血管性认知障碍/游离三碘甲状腺原氨酸/影响因素Key words
Vascular cognitive impairment/Free triiodothyronine/Inlfuencing factors引用本文复制引用
马洪颖,李瑜霞,李永秋,刘春芹,张冬森,王丽英,高轩,高海凤,付子娟..非痴呆性血管性认知障碍的影响因素研究[J].中国卒中杂志,2017,27(1):18-22,5.
