中国卒中杂志2017，Vol.27Issue(1)：29-33,5.DOI:10.3969/j.issn.1673-5765.2017.01.005
磁共振弥散加权像阴性缺血性卒中临床特征和原因分析
The Analysis of Clinical Characteristics and Cause of Magnetic Resonance Imaging Diffusion-weighted Imaging Negative Stroke
陈蕾 1朱宣 1张萍 1张敏敏 1于龙娟 1张永巍 1吴涛 1邓本强1
作者信息
- 1. 200433 上海第二军医大学长海医院脑血管病中心
- 折叠
摘要
Abstract
Objective To identify the different clinical characteristics between diffusion-weighted imaging negative and positive stroke treated with intravenous thrombolysis and analyse the cause of diffusion-weighted imaging (DWI) negative stroke. Methods Retrospective analysis was made upon data of patients with ischemic stroke who received intravenous thrombolysis during September 2013 and February 2015. The patients were divided into DWI positive group and DWI negative group based on head magnetic resonance imaging (MRI). The differences in baseline data, risk factors for cerebral vascular diseases, clinical manifestation and outcome at discharge were compared between the two groups. Results Among 119 patients, there were 94 cases of DWI positive and 25 cases of DWI negative with 21% of DWI negative rate. There were no obvious differences between the baseline characteristics of DWI negative stroke versus DWI positive stroke, including gender, age and risk factor for cerebral vascular diseases. No inter-group differences in NIHSS score were noted at admission NIHSS. The discharge NHISS of DWI negative stroke was 0 (0, 1) which was obviously lower than that of DWI positive group's 1 (0, 4) (P=0.02). The discharge mRS of DWI negative stroke was 0 (0, 1) while DWI positive stroke was 1 (1, 3) (P<0.001). There were significantly statistical differences between them. The hemorrhagic transformation rate (2.1%) and mortality rate (1.1%) of DWI positive stroke were relatively low, and there were no hemorrhagic transformation or death occurring in DWI negative group. There were no obvious differences in hemorrhagic transformation or death outcome. Conclusion DWI negative stroke is milder and recover better than DWI positive stroke. As the intracranial hemorrhage rate and mortality are low in either DWI positive or negative stroke, rt-PA intravenous thrombolysis is safe in stroke.关键词
弥散加权成像/阴性/缺血性卒中/静脉溶栓/临床特点Key words
Diffusion-weighted imaging/Negative/Stroke/Intravenous thrombolysis/Clinical characteristics引用本文复制引用
陈蕾,朱宣,张萍,张敏敏,于龙娟,张永巍,吴涛,邓本强..磁共振弥散加权像阴性缺血性卒中临床特征和原因分析[J].中国卒中杂志,2017,27(1):29-33,5.
