中华灾害救援医学2017,Vol.5Issue(2):65-67,3.DOI:10.13919/j.issn.2095-6274.2017.02.002
8·12天津爆炸后受伤消防战士甲状腺激素水平变化
Variation of serum thyroid hormone levels in ifre ifghters injured in the 8•12 Tianjin explosion
王秀梅 1张金红 1丁琪 1杨晓莉 1郝钦芳 1王峥辉 1肖晓军 1宋丽洁1
作者信息
摘要
Abstract
Objective The aim of this study was to investigate the variation of serum thyroid hormone levels in fire fighters injured in the explosion on 8·12 in Tianjin, and to explore the relationship between the thyroid hormone and stress. Methods Total-triiodothyronine (TT3), total thyroxine (TT4), free triiodothyronine (FT3), free thyroxine (FT4) and thyroid-stimulating hormone (TSH) levels of fire fighters before and after injury were analyzed with an immunology analyzer, Johnson Vitros 3600 from America. Results Serum thyroid hormone levels of fire fighters before and after injury as well as at different time points were compared. The results showed statistically significant differences across all time points in TT3 (F=85.95, P<0.05), TT4 (F=27.98, P<0.05), FT3 (F=14.89, P=0.001), FT4 (F=11.96, P<0.05);but the difference in TSH was not significant (F=1.99, P=0.164). The order of degree of variation of the fire fighters' thyroid hormone levels soon after injury was sorted as TSH>T3>FT4>T4>FT3, 24 h after injury it was TSH>FT4>FT3>T3>T4, and TSH>T4>FT3>FT4>T3 48 h after injury. Conclusions Thyroid hormones are involved in the stress response of injured fire fighters, and TT3, TT4, FT3, FT4 can be used as indicators of trauma stress response.关键词
应激/甲状腺激素Key words
stress/thyroidhormones分类
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王秀梅,张金红,丁琪,杨晓莉,郝钦芳,王峥辉,肖晓军,宋丽洁..8·12天津爆炸后受伤消防战士甲状腺激素水平变化[J].中华灾害救援医学,2017,5(2):65-67,3.