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超顺磁性氧化铁纳米颗粒标记干细胞的研究进展

张昕桐(综述) 熊猛(审校)

组织工程与重建外科杂志2016,Vol.12Issue(6):378-380,3.
组织工程与重建外科杂志2016,Vol.12Issue(6):378-380,3.DOI:10.3969/j.issn.1673-0364.2016.06.014

超顺磁性氧化铁纳米颗粒标记干细胞的研究进展

Research Progress of Superparamagnetic Iron Oxide Nanoparticles on Labeling Stem Cells

张昕桐(综述) 1熊猛(审校)1

作者信息

  • 1. 210009 江苏省南京市 东南大学附属中大医院烧伤整形科
  • 折叠

摘要

Abstract

[Summary] Superparamagnetic iron oxide nanoparticles (SPIONs) are a kind of nano materials which have broad application prospects in the field of labeling cells, targeted drug delivery and heat treatment of tumor. Especially in regenerative medicine, more and more research and application of stem cells have been founded. SPIONs have provided a new method to label and track cells. The characteristics of SPIONs are superparamagnetic, low toxicity, good biocompatibility and directional movement in the magnetic field. SPIONs present low signal area in magnetic resonance imaging (MRI) and they can label cells safely and effectively with appropriate coatings. But the uncertainty of cytotoxicity and the limitation of MRI are still unsolved. In this paper, the research progress of SPIONs in labeling cells were reviewed.

关键词

超顺磁性氧化铁/干细胞/标记

Key words

Superparamagnetic iron oxide nanoparticles/Stem cells/Labeling

分类

生物科学

引用本文复制引用

张昕桐(综述),熊猛(审校)..超顺磁性氧化铁纳米颗粒标记干细胞的研究进展[J].组织工程与重建外科杂志,2016,12(6):378-380,3.

组织工程与重建外科杂志

OACSTPCD

1673-0364

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