腹腔镜外科杂志2017，Vol.22Issue(1)：53-57,5.DOI:10.13499/j.cnki.fqjwkzz.2017.01.053
腹腔镜与开腹全胃切除联合D2淋巴结清扫术治疗进展期胃癌的疗效比较
Comparisons of clinical efficacy between laparoscopic and open total gastrectomy combined with D2 lymph node dissection for patients with advanced gastric carcinoma
摘要
Abstract
Objective:To compare the clinical efficacy between laparoscopic and open total gastrectomy combined with D2 lymph node dissection for patients with advanced gastric carcinoma. Methods:Clinical data of 196 patients with advanced gastric carci-noma treated by total gastrectomy combined with D2 lymph node dissection from May 2009 to May 2011 were retrospectively analyzed. They were divided into laparoscopic group (n=72) and open group (n=124),laparoscopic group underwent laparoscopic total gastrec-tomy combined with D2 lymph node dissection and open group underwent open total gastrectomy combined with D2 lymph node dissec-tion. The clinical index,complications and long-term survival rate of the two groups were compared. Results:The operative time in lapa-roscopic group was significantly longer than that in open group (P<0. 05),and the intraoperative blood loss,first exhaust time,recovery time of gastrointestinal function and hospitalization time in laparoscopic group were significantly less than those in open group ( P<0. 05). No statistically significant differences in the number of lymph nodes,tumor proximal and distal margin and hospitalization cost be-tween two groups were found. The postoperative complication rate in laparoscopic group was 2. 8%,which was lower than that in open group (12. 9%,P<0. 05). There were no significant differences in tumor free survival rate and overall survival rate after 1 year,3 years and 5 years between the two groups (P>0. 05). Conclusions:Compared with open surgery,laparoscopic total gastrectomy combined with D2 lymph node dissection for patients with advanced gastric carcinoma has characteristics of faster recovery,fewer complications, and no statistically significant difference in the number of harvested lymph nodes and long-term survival rate.关键词
胃肿瘤/胃切除术/腹腔镜检查/剖腹术/淋巴结切除术/疗效比较研究Key words
Stomach neoplasms/Gastrectomy/Laparoscopy/Laparotomy/Lymph node excision/Comparative effectiveness re-search分类
医药卫生引用本文复制引用
校智祥,赵刚,唐元明..腹腔镜与开腹全胃切除联合D2淋巴结清扫术治疗进展期胃癌的疗效比较[J].腹腔镜外科杂志,2017,22(1):53-57,5.
