口腔疾病防治2017，Vol.25Issue(2)：123-128,6.DOI:10.12016/j.issn.2096-1456.2017.02.012
环状RNA研究进展及其在口腔疾病中的研究展望
Research progress of circular RNA and its research prospects in oral diseases
摘要
Abstract
Circular RNAs (circRNAs) are RNAs with a covalently closed loop structure, characterized by its conser⁃vation, stability, tissue specific and ubiquity. CircRNAs can serve as miRNA‘sponges’to modulate the mRNA targets of miRNAs. CircRNAs can bind with RNA binding proteins and regulate the expression of some genes. The differential expression of circRNAs between pathogenic and normal tissues makes circRNAs possibly promising biomarkers for diag⁃nosis and targets for treatment. In this article, we reviewed the research progress of circRNA and discussed its research prospects in oral diseases.关键词
环状RNA/肿瘤/口腔病/miRNA海绵体/生物标志物Key words
Circular RNA/Tumor/Oral diseases/miRNA sponge/Biomarker分类
医药卫生引用本文复制引用
曾秉辉(综述),余东升(审校)..环状RNA研究进展及其在口腔疾病中的研究展望[J].口腔疾病防治,2017,25(2):123-128,6.基金项目
国家自然科学基金（81272554、81472526）；广东省科技计划项目 （）
