中国实用神经疾病杂志2017，Vol.20Issue(3)：24-25,2.
慢性硬膜下血肿患者D-二聚体检测的意义及氨甲苯酸术中冲洗血肿腔对其复发的影响
Significance of D-dimer in the patients with chronic subdural hematoma and the effect of the irrigation on the re-currence of the patients with chronic subdural hematoma
王晓东 1丁赵琦 1金振萼 1金诗敏 1王晓平 1袁坚1
作者信息
- 1. 上海市嘉定区中心医院神经外科 上海 201800
- 折叠
摘要
Abstract
Objective To determine the content of D-dimer in peripheral blood and hematoma fluid of patients with chronic subdural hematoma,and to study the effect of the use of aminomethylbenzoic acid with irrigation treatment in burr hole drainage on the recurrence of CSDH.Methods Forty-nine patients with CSDH were randomly divided into experimental group and control group,the content of D-dimer in peripheral venous plasma and hematoma fluid was measured,and aminomethylbenzoic acid was used to irrigate hematoma cavity in the experiment group,while physiological saline was used to irrigate hematoma cavity in the control group,postoperative follow-up for 3 months and the recurrence rate was compared.Results There was no difference in the content of D-dimer in peripheral blood and hematoma fluid of two groups in the experimental group and control group(P>0.05). Self control of CSDH patients,D-dimer in hematoma fluid increased significantly than that in peripheral blood(P<0.01).The re-currence rate of the experimental group was lower than that of the control group(P<0.05).Conclusion D-dimer may play an im-portant role in the pathogenesis of CSDH.Aminomethylbenzoic acid can inhibit fibrinolysis and irrigating the hematoma cavity can reduce the recurrence of CSDH.关键词
慢性硬膜下血肿/D-二聚体/氨甲苯酸/复发Key words
Chronic subdural hematoma/D-dimer/Aminomethylbenzoic acid/Recurrence分类
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王晓东,丁赵琦,金振萼,金诗敏,王晓平,袁坚..慢性硬膜下血肿患者D-二聚体检测的意义及氨甲苯酸术中冲洗血肿腔对其复发的影响[J].中国实用神经疾病杂志,2017,20(3):24-25,2.
