检验医学与临床2016,Vol.13Issue(z2):142-145,4.DOI:10.3969/j.issn.1672-9455.2016.26.061
免疫组织化学法与流式细胞术在非小细胞肺癌骨髓微转移检测中的效果
The effect of immunohistochemistry and flow cytometry on the detection of bone marrow micro metastasis in patients with non small cell lung cancer
摘要
Abstract
Objective To compare the difference of the bone marrow micro metastasis of non small cell lung cancer by immuno-histochemistry and flow cytometry .Methods in May 2009 to March 2011 in our hospital surgical treatment of non small cell lung cancer (NSCLC) 160 cases ,preoperative without going through chemotherapy and radiotherapy ,surgery in selected rib bone mar-row ,respectively ,and the application of immunohistochemistry and flow cytometry detection of bone marrow in positive cells ex-pression rate .Results 160 cases of immune system in patients with non small cell lung cancer group of detection of bone marrow metastasis positive rate was 30 .0% (48 cases) and stream cytometry bone marrow metastasis positive rate was 34 .4% (55 cases) , 112 cases of immunohistochemical examination negative patients in ,flow cytometry found that 12 patients with bone marrow occur-ring micrometastasis ;and 48 cases of immunohistochemical examination positive patients ,5 patients with flow cytometry was nega-tive .Conclusion both flow cytometry and immunohistochemical technique can detect the bone marrow micro metastasis of non small cell lung cancer ,and flow cytometry has a higher sensitivity and detection efficiency .关键词
免疫组织化学法/流式细胞术/非小细胞肺癌/骨髓微转移Key words
immunohistochemical method/flow cytometry/non small cell lung cancer/bone marrow micro metastasis引用本文复制引用
郑小江,黄其文,李春晓..免疫组织化学法与流式细胞术在非小细胞肺癌骨髓微转移检测中的效果[J].检验医学与临床,2016,13(z2):142-145,4.