摘要
Abstract
Objective To explore the influencing factors of quality of life and family burden in patients with Alzheimer′s disease . Methods This study is a cross‐sectional study ,84 AD patients and their caregivers were selected from People′s Hospital of Chang‐shou Chongqing as the research object .Their qualities of life were evaluated by Quality of Life‐Alzheimer′s Disease(QOL‐AD) , Family Burden were evaluated by Caregiver Burden Inventory (CBI) and the Family Burden Scale(FBS) .The analysis of variance and t test were applied in comparing the intergroup difference of measurement data .Pearson correlation analysis were applied in comparing the relationship between the quality of life score ,family caregiver burden score and the patient factors .Multiple linear re‐gression model were applied to analyze the factors affecting the quality of life of patients and caregiver burden .Results AD patients quality of life scores for(30 .8 ± 4 .8) ,each factor score from high to low in order for :energy ,family relationships ,emotion ,on their overall feeling ,physical health status ,life of overall situation ,entertainment and ability ,economic status ,living environment ,do the housework ability ,friend relationship ,marital status and memory .Total score of CBI for(53 .4 ± 17 .3) ,caregiver burden factor or‐der as follows :development limited burden ,body burden ,emotional burden ,time dependent burden and social burden .FBS score for (17 .2 ± 9 .8) ,family burden factor order as follows :the daily family activity ,family economic burden ,family entertainment ,family relationship ,family members of the body health and mental health of family members ,which in addition to the family members of physical health and mental health were moderate burden .Between AD patients quality of life and the burden of caregivers (r= - 0 .232 ,P= 0 .013) and family burden of the caregivers (r = - 0 .229 ,P= 0 .005) showed a negative correlation .Multivariate analysis showed that :(according to the influence degree of order ) with the degree of dementia ,ability of daily living and quality of life ;have an influence on the total score of family burden of the caregivers of FBS factors (according to the influence degree of order ) quality of life and the dementia process of factors impact on caregiver burden CBI scores .Conclusion The quality of life of patients with AD is generally low ,ability the effects of AD patients with the degree of dementiaof daily living and quality of life caregivers and family burden greatly .关键词
阿尔茨海默病/生存质量/照料者/家庭负担/影响因素Key words
Alzheimer′s disease/quality of life/caregivers/family burden/influencing factors