世界中医药2016，Vol.11Issue(12)：2658-2660,2664,4.DOI:10.3969/j.issn.1673-7202.2016.12.035
芪参益气滴丸对糖尿病早期肾病患者血 SSA、IL-6及 TNF-α的影响
Effect of Ginseng and Astragalus Qi-Replenishing Drop Pill on Early Diabetic Nephropathy Patients′SSA,IL-6 and TNF-αlevels
摘要
Abstract
Objective:To discuss the effect of Ginseng and Astragalus Qi-Replenishing Drop Pill on early diabetic nephropathy pa-tients′serum amyloid protein(SSA),interleukin 6 (IL-6)and tumor necrosis factor-α(TNF-α)levels.Methods:Early diabetic nephropathy 100 patients were retrospectively analyzed from September 2012 to December 2015 in our Hospitals.According to the treatment,all patients were divided into pill group and control group,50 cases in each group,control group patients were given regular diet control,insulin hypoglycemic therapy.On its basis,the pill group were given 500 mg of Ginseng and Astragalus Qi-Replenishing Drop Pill.The enzyme-linked immunosorbent (ELISA)was used to detect serum SSA,IL-6 and TNF-αlevel,fol-lowed up for 6 months.All patients′index levels,before and after treatment 1,3,6 months′urine beta 2 microglobulin (β2-MG), urinary albumin excretion rate (UAER)and adverse reactions were observed.Results:After the treatment,the pill group′s serum SSA,IL-6 and TNF-αlevel were significantly lower than the control group (P <0.05);Pill group patients′1,3,6 months β2-MG,UAER levels were significantly lower than the control group (P <0.05);Pill group and control group had no adverse reac-tions.Conclusion:Ginseng and Astragalus Qi-Replenishing Drop Pill can effectively improve the inflammatory state in patients with early diabetic nephropathy,reduce the excretion of urine albumin of patients with safety,which is worthy of further clinical promotion.关键词
芪参益气滴丸/糖尿病/早期肾病Key words
Ginseng and Astragalus Qi-Replenishing Drop Pill/Diabetes/Early stage Nephropathy分类
医药卫生引用本文复制引用
卿照前,王松涛,张国强,谭秦湘..芪参益气滴丸对糖尿病早期肾病患者血 SSA、IL-6及 TNF-α的影响[J].世界中医药,2016,11(12):2658-2660,2664,4.基金项目
长沙市科技局资助项目 （）
