疏肝健脾法治疗腹泻型肠易激综合征肝郁脾虚证的临床观察及对血清脑肠肽水平的影响OACHSSCDCSTPCD
Clinical Observation on therapy of Soothing the Liver and Strengthening the Spleen in Diarrhea-Predominant Irritable Bowel Syndrome(IBS-D)of Liver Depression and Spleen Deficiency Syndrome and Its Influence on Serum Brain-gut Peptide Level
目的：探讨疏肝健脾法治疗腹泻型肠易激综合征（IBS-D）肝郁脾虚证的临床效果及对血清脑肠肽水平的影响。方法：将70例 IBS-D 患者随机分为观察组（n ＝35）和对照组（n ＝35），对照组采用常规西药进行治疗，观察组在此基础上增加自制疏肝健脾汤进行治疗，2组均治疗4周。比较治疗前后2组血清5-羟色胺（5-HT）、降钙素基因相关肽（CGRP）、血清 P 物质（SP）及神经肽 Y（NPY）水平及中医症状积分变化，统计2组临床有效率及复发情况。结果…查看全部>>
Objective:To investigate the clinical effect of soothing the liver and strengthening the spleen therapy on diarrhea-pre-dominant irritable bowel syndrome (IBS-D)of liver depression and spleen deficiency syndrome and its effect on serum brain-gut peptide level.Methods:Seventy patients with IBS-D were randomly divided into an observation group (n =35 )and a control group (n =35).The control group was treated with conventional western medicine,and the observati…查看全部>>
汪正芳;贾玉;侯亚男
首都医科大学附属北京中医医院，北京，100010北京中医药大学第三附属医院，北京，100029首都医科大学附属北京中医医院，北京，100010
医药卫生
肠易激综合征疏肝健脾法肝郁脾虚证脑肠肽
Irritable bowel syndromeShuganjianpi therapyLiver depression and spleen deficiency syndromeBrain-gut pep-tide
《世界中医药》 2016 (12)
2685-2688,4
国家自然科学基金青年项目（编号81302949）；北京市中医药科技发展资金项目（编号JJ2014-35）；北京市医院管理局“青苗”计划专项经费资助（编号QML20150902）
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