山西医科大学学报2017，Vol.48Issue(1)：65-68,4.DOI:10.13753/j.issn.1007-6611.2017.01.015
超声引导下不同浓度罗哌卡因臂丛神经阻滞心脏毒性的比较
Comparison of cardiotoxicity between different concentrations of ropivacaine for brachial plexus block under the guidance of ultrasound
陈慧清 1高东艳 2任伟侠1
作者信息
- 1. 山西医科大学麻醉学系麻醉科，太原 030001
- 2. 山西医科大学第二医院麻醉科
- 折叠
摘要
Abstract
Objective To compare the cardiotoxicity between different concentrations of ropivacaine applied to brachial plexus block under the guidance of ultrasound. Methods Sixty patients with ASAⅠ-Ⅱundergoing elective forearm or hand surgery were ran-domly divided into three groups:0. 33% ropivacaine group,0. 40% ropivacaine group,0. 50% ropivacaine group. Axillary brachial plexus was blocked under the guidance of ultrasound, the onset time of analgesia, duration of analgesia, block effect, function recovery time and incidence of adverse reactions were recorded. Four milliliters blood samples were taken from veins of the patients for determi-ning the serum cTnI and CK-MB before anesthesia and 24 h after drug injection. Results With the increase of concentration of ropiv-acaine,the onset time became shorter,and the duration of analgesia and function recovery time became longer. The effects of brachial plexus block showed no statistically significant difference between the groups. No adverse reaction occurred in three goups. The cTnI, CK-MB levels increased at 24 h after drug injection. The cTnI,CK-MB levels increased with the increase of concentration of ropiva-caine, and there was significant difference between the groups(P<0. 05). Conclusion The 0. 33% -0. 50% ropivacaine can meet the requirement of axillary brachial plexus block under the guidance of ultrasound, but the cardiotoxicity may increase in a concentra-tion-dependent manner. Considering onset time of analgesia, duration of analgesia,function recovery time and cardiotoxicity, 0. 4%ropivacaine may be recommended for ultrasound-guided brachial plexus block.关键词
罗哌卡因/超声引导/臂丛神经阻滞/心脏毒性Key words
ropivacaine/ultrasound guide/brachial plexus block/cardiotoxicity分类
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陈慧清,高东艳,任伟侠..超声引导下不同浓度罗哌卡因臂丛神经阻滞心脏毒性的比较[J].山西医科大学学报,2017,48(1):65-68,4.
